The effects of oral ginseng administration on the activities and isoenzyme profiles of murine lactate dehydrogenases

Harper, Nicola; Osborne, Allison; Makov, Udi; Bittles, Alan H.

doi:10.1016/0006-2952(84)90434-9

Cited by 3 publications

(1 citation statement)

References 17 publications

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“…Since LDH is important enzyme in the carbohydrate metabolism and related to energy production in the living cell, the induced activity level in the haemolymph of nymphs of S. gregaria, in the present study, indicates generally an active energy metabolism in this important tissue. It, also, may indicate an effective stimulation of the portion of the Cori cycle responsible for the overall recycling lactate, since this would result in concomitant enhanced production of pyruvate and glucose via glucogenesis (Harper et al, 1984).…”

Section: ) Disturbed Ldh Activity In the Haemolymphmentioning

confidence: 99%

Alterations in the lactate dehydrogenase activity of the desert locust Schistocerca gregaria by the wild plant Fagonia bruguieri (Zygophyllaceae).

Sh.

Basiouny

Ghoneim

2010

Egyptian Academic Journal of Biological Sciences. A, Entomology

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The wild plant F. bruguieri extracts caused some alterations in the lactate dehydrogenase activity in haemolymph and fat body of the last instar nymphs and newly emerged adults of the desert locust S. gregaria. Each of two concentration levels of methanolic (7.5 and 3.7%), petroleum ether (30.0 and 15.0%) or n-butanolic extract (30.0 and 15.0%) was applied against the penultimate instar nymphs through the fresh clover leaves, Medicago sativa, as a food.Unexceptionally, all F. bruguieri extracts induced the LDH activity in the haemolymph along the nymphal instar, irrespective of the solvent or concentration level. The strongest inducing effect was exhibited in the mid-aged nymphs (62601.3±467.4 U/L in comparison with 53696.8±467.4 U/L of control congeners) after treatment with the higher concentration level of methanolic extract. On the contrary, the LDH activity was significantly prohibited in the newly emerged adults. The most drastically inhibited enzyme activity was determined (57744.3±467.4 U/L, compared to 62871.2±934.7 U/L of control congeners) after nymphal treatment with higher concentration level of n-butanolic extract.With regard to the fat body, all F. bruguieri extracts prohibited LDH activity along the nymphs instar, irrespective of the concentration level. The most dramatically reduced activity was expressed in (9166.4±119.0 U/L vs. 22839.5±289.1 U/L of control congeners) after treatment with the lower concentration level of nbutanolic extract. In contrast, the plant extracts pronouncedly enhanced the enzyme activity in the fat body of adults, regardless to the extract. The most stimulatory effect was exhibited after treatment of the nymphs with the lower concentration level of nbutanolic extract.

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Section: ) Disturbed Ldh Activity In the Haemolymphmentioning

confidence: 99%

Alterations in the lactate dehydrogenase activity of the desert locust Schistocerca gregaria by the wild plant Fagonia bruguieri (Zygophyllaceae).

Sh.

Basiouny

Ghoneim

2010

Egyptian Academic Journal of Biological Sciences. A, Entomology

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2013

Principles and Practice of Phytotherapy

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The chemistry and biological significance of saponins in foods and feedingstuffs

Price¹,

Johnson²,

Fenwick³

et al. 1987

C R C Critical Reviews in Food Science and Nutrition

582

321

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Saponins occur widely in plant species and exhibit a range of biological properties, both beneficial and deleterious. This review, which covers the literature to mid 1986, is concerned with their occurrence in plants and their effects when consumed by animals and man. After a short discussion on the nature, occurrence, and biosynthesis of saponins, during which the distinction between steroidal and triterpenoid saponins is made, the structures of saponins which have been identified in a variety of plants used as human foods, animal feedingstuffs, herbs, and flavorings are described. Many of these compounds have been characterized only during the last 2 decades, and modern techniques of isolation, purification, and structural elucidation are discussed. Particular consideration is given to mild chemical and enzymatic methods of hydrolysis and to recent developments in the application of NMR and soft ionization MS techniques to structural elucidation. Methods currently used for the quantitative analysis of saponins, sapogenols, and glycoalkaloids are critically considered; advances in the use of newer methods being emphasized. The levels of saponins in a variety of foods and food plants are discussed in the context of the methods used and factors affecting these levels, including genetic origin, agronomic, and processing variables, are indicated. Critical consideration is given to the biological effects of saponins in food which are very varied and dependent upon both the amount and chemical structure of the individual compounds. The properties considered include membranolytic effects, toxic and fungitoxic effects, adverse effects on animal growth and performance, and the important hypocholesterolemic effect. A final section deals briefly with the pharmacological effects of saponins from ginseng, since use of this plant is increasing in certain sections of western society as well as being traditional in the Orient.

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The effects of oral ginseng administration on the activities and isoenzyme profiles of murine lactate dehydrogenases

Cited by 3 publications

References 17 publications

Alterations in the lactate dehydrogenase activity of the desert locust Schistocerca gregaria by the wild plant Fagonia bruguieri (Zygophyllaceae).

Alterations in the lactate dehydrogenase activity of the desert locust Schistocerca gregaria by the wild plant Fagonia bruguieri (Zygophyllaceae).

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The chemistry and biological significance of saponins in foods and feedingstuffs

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