The effects of maternal narcotic addiction on the newborn

Goodfriend, Milton J.; Shey, Irving Alfred; Klein, Milton D.

doi:10.1016/0002-9378(56)90674-3

Cited by 84 publications

(12 citation statements)

References 2 publications

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“…A pa¬ tient last seen at 17 months had clumsy, asymmetrical hand use, toe stance, and slight delay of gross mo¬ tor development. A (4) Follow-up of the in¬ fant is dependent upon the coopera¬ tion of the addict parent or, more commonly, cooperation of the rela¬ tives or court-appointed foster par¬ ents raising the child. The period of "subacute with¬ drawal" symptoms has been impres¬ sive for several reasons.…”

Section: Resultsmentioning

confidence: 99%

Early Development of Infants of Heroin-Addicted Mothers

Wilson¹

1973

Arch Pediatr Adolesc Med

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The course of growth and development of 30 infants of heroin addicts was observed from 3 to 34 months.Eighty percent had signs of neonatal withdrawal, while 60% continued with subacute withdrawal signs for three to six months.Behavioral disturbances, predominantly hyperactivity, brief attention span, and temper outbursts, were identified in seven of 14 infants observed one year or longer, while two had neurological abnormality. Growth impairment was associated with behavioral disturbances in four of the seven. These disturbances appear to be unrelated to subsequent environmental factors.Infants performed at age-appropriate levels on developmental testing.

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Section: Resultsmentioning

confidence: 99%

Early Development of Infants of Heroin-Addicted Mothers

Wilson¹

1973

Arch Pediatr Adolesc Med

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“…A growth in the occurrence of morphine and heroin habit among females was prominent as early as about 100 years ago (4); but, newborns were not believed to be exposed as it was supposed that morphine use amongst females was related to infertility and damage of erotic desire. That misconception modified since the initial described event in a neonate about 1987 (5,6) who displayed signs of opioid withdrawal at delivery, identified by means of inherited morphinism. After that, augmented reports of congenital morphinism caused an important consideration in the view of obstetricians and pediatricians (6,7).…”

Section: Contextmentioning

confidence: 99%

“…That misconception modified since the initial described event in a neonate about 1987 (5,6) who displayed signs of opioid withdrawal at delivery, identified by means of inherited morphinism. After that, augmented reports of congenital morphinism caused an important consideration in the view of obstetricians and pediatricians (6,7). Inherited morphinism was situated afterward retitled in place of abstinence syndrome in neonates.…”

Section: Contextmentioning

confidence: 99%

A Review of Neurobehavioral Challenges in Children Exposed Prenatally to Intrauterine Opioid

Alaedini¹,

Haddadi²,

Asadian³

2017

J Pediatr Rev

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Context: Substance abuse has remained a worldwide issue for many years and in recent decades there has been a major growth in the number of individuals consuming opioids. Several studies have discovered that young kids who have been exposed to opioids develop greater damages in overall intellectual capabilities and neurobehavioral functions than non-exposed children. Evidence Acquisition: The purpose of this study was to evaluate the surviving texts on the incidence of challenging behavior among kids due to prenatal medication contact. Overall, out of 84 identified manuscripts, 18 were established to consider intellectual, psychomotor, and behavior consequences in opioid-exposed infants, precollege and college children when matched with healthy no-opioid-exposed controls. Results:The results indicate that children exposed to opioid in utero may be cognitively affected over time, even once located in stable families on an actual early age. Somewhat, susceptibilities seem to rise by age for girls, and the unprotected boys persist behind non exposed boys entirely through infancy and into college age. Therefore, there looks to be a constant deleterious consequence of factors associated with prenatal medication contact over time. Conclusions:The results indicate children exposed to opioid in utero may be cognitively affected over time, even once located in stable families on an actual early age. The natural susceptibilities of prenatally drug-exposed children can affect initial intellectual skills which yet again are extremely associated with advanced mental capabilities. It is feasible that pre-and postnatal genetic susceptibilities and ecological issues cooperate in a transactional method through the child's lifespan.

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“…However, the attention of the medical profession was drawn particularly by Perlstein (1947) when he reported neonatal narcotic addiction as a cause of seizures. Since that time, there have been many reports of fetal narcotic addic tion (Cobrinik, 1956;Cobrinik et al, 1959\Dikshit, 1961Goodfriend et al, 1956;Hill and Desmond, 1963;Kahn et al, 1969;Krause et al, 1958;Kunstadter et al, 1958;Perlmutter, 1947;Perlstein, 1947;Roman and Middlekamp, 1958;Rosenthal et al, 1965, Schneck, 1958Slobody and Cobrinik, 1971 ;Steg, 1957;Zelson, 1973), including that of Claman and Strang (1962) from Canada. 75-85 % of the babies born of addicted mothers show drug withdrawal symptoms [Zelson, 1973).…”

Section: Withdrawal Symptoms Opiatesmentioning

confidence: 99%

Side Effects on Fetus and Infant of Psychotropic Drug Use during Pregnancy

Ananth¹

1976

Int Pharmacopsychiatry

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Psychotropic drugs are used frequently for the treatment of emotional as well as other disorders. With usage so widespread, many pregnant women receive psychotropic drugs. Maternal ingestion of these drugs may produce, in the fetus, side effects including withdrawal symptoms. Withdrawal signs in the fetus as a result of maternal intake of opiates, hypnotics, analgesics, and tricyclic antidepressant drugs have been reported. Fetal side effects can occur by maternal ingestion of nuroleptic medications, lithium, antidepressants, anxiolytic sedatives, anticonvulsants, and bromides. The author feels that even though these drugs are generally safe, they must only be administered to pregnant women when absolutely needed, and then under vigilance.

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The effects of maternal narcotic addiction on the newborn

Cited by 84 publications

References 2 publications

Early Development of Infants of Heroin-Addicted Mothers

Early Development of Infants of Heroin-Addicted Mothers

A Review of Neurobehavioral Challenges in Children Exposed Prenatally to Intrauterine Opioid

Side Effects on Fetus and Infant of Psychotropic Drug Use during Pregnancy

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