The effects of live yeast Saccharomyces cerevisiae on postweaning diarrhea, immune response, and growth performance in weaned piglets1,2

Abstract

The effects of live yeast Saccharomyces cerevisiae (strain CNCM I-4407, 10(10) cfu/g; Actisaf; Lesaffre Feed Additives, Marcq-en-Baroeul, France) on the severity of diarrhea, immune response, and growth performance in weaned piglets orally challenged with enterotoxigenic Escherichia coli (ETEC) strain O149:K88 were investigated. Live yeast was fed to sows and their piglets in the late gestation, suckling, and postweaning periods. Sows were fed a basal diet without (Control; n = 2) or with (Supplemented; n = 2) 1 g/kg of live yeast from d 94 of gestation and during lactation until weaning of the piglets (d 28). Suckling piglets of the supplemented sows were orally treated with 1 g of live yeast in porridge carrier 3 times a week until weaning. Weaned piglets were fed a basal starter diet without (Control; n = 19) or with (Supplemented; n = 15) 5 g of live yeast/kg feed for 2 wk. Significantly lower daily diarrhea scores (P < 0.05), duration of diarrhea (P < 0.01), and shedding of pathogenic ETEC bacteria (P < 0.05) in feces was detected in the supplemented piglets. Administration of live yeast significantly increased (P < 0.05) IgA levels in the serum of piglets. Evidence indicates that decreased infection-related stress and severity of diarrhea in yeast-fed weaned piglets positively affected their growth capacity in the postweaning period (P < 0.05). The results suggest that dietary supplementation with live yeast S. cerevisiae to sows and piglets in the late gestation, suckling, and postweaning periods can be useful in the reduction of the duration and severity of postweaning diarrhea caused by ETEC.

Effect of dietary supplementation with brewer's yeast hydrolysate on growth performance, faecal microbial counts, diarrhoea score, blood profile, rectal temperature in weanling pigs challenged with lipopolysaccharide

“…Post‐weanling diarrhoea is one of the principal problems faced by the pig industry. Trckova et al () studied the effects of live yeast S. cerevisiae on post‐weanling diarrhoea in weaned piglets and found that feeding live yeast S. cerevisiae can significantly reduce the diarrhoea of piglets, which is consistent with our study at 2nd week that Piglets fed brewer's yeast hydrolysed have low diarrhoea score after the LPS challenged.…”

Post weaning diarrhea in pigs: risk factors and non-colistin-based control strategies

“…Decreased diarrhea A combination of phages is needed F4 in experimental PWD [130]. In addition, it was shown that the feeding of pigs with live yeast Saccharomyces cerevisiae enhanced their growth and reduced the duration and the severity of PWD caused by ETEC [131]. It has been demonstrated that the administration of a mixture of two probiotics, Pediococcus acidilactici and Saccharomyces cerevisiae boulardii, in the feed of challenged weaned pigs reduced ETEC: F4 attachment to the ileal mucosa in comparison with the group treated with chlortetracycline and tiamulin [103].…”

Saccharomyces cerevisiaeas a probiotic feed additive to non and pseudo‐ruminant feeding: a review

“…Indeed, pigs that were challenged with E. coli K88 and fed diets containing a yeast fermentation product have higher concentrations of serum tumour necrosis factor‐alpha, less diarrhoea, higher appetite and decreased adherence of E. coli to the intestinal mucosa than pigs fed an un‐supplemented control (Kiarie et al , ). Likewise, pigs fed on diets supplemented with live yeast and exposed to enterotoxigenic E. coli were observed to have reduced disease‐related stress, reduced diarrhoea scores, reduced duration of diarrhoea, and reduced shedding of E. coli (Trckova et al ). Jiang et al () reported that feeding of live yeast and finely ground live yeast increases serum concentrations of IgA, IL‐2 and IL‐6.…”