The effects of lesion baseline characteristics and different Sr:Ca ratios in plaque fluid-like solutions on caries lesion de- and remineralization

Lippert, Frank

doi:10.1016/j.archoralbio.2012.08.012

Cited by 7 publications

(8 citation statements)

References 40 publications

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“…All specimens were pH-cycled for 10 days using an established pH-cycling model based on White [18], however, a daily 4-hour rather than 2-hour acid challenge in the demineralization solution was used. Treatments were performed with either a sodium fluoride solution (367 ppm F simulating a 1100 ppm F dentifrice after 1:2 dilution -groups 24 h/a, 48 h/a and 96 h/a) or deionized water (groups 24 h/b, 48 h/b and 96 h/b), with storage in artificial saliva (2.20 g/L gastric mucin, 1.45 mmol/L CaCl2 • 2 H2O, 5.42 mmol/L KH2PO4, 6.50 mmol/L NaCl, 14.94 mmol/L KCl) all other times. The pH of the artificial saliva was adjusted to 7.0 using KOH [19].…”

Section: Ph-cyclingmentioning

confidence: 99%

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The influence of hardness and chemical composition on enamel demineralization and subsequent remineralization

Alkattan

Lippert

Tang

et al. 2018

Journal of Dentistry

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Section: Ph-cyclingmentioning

confidence: 99%

“…Dental caries is a dynamic process that involves alternating demineralization and remineralization cycles. Several studies have reported that baseline physical and chemical characteristics of enamel greatly influence its behavior in such de-and subsequent remineralization challenges [4,5,6].…”

Section: Introductionmentioning

confidence: 99%

The influence of hardness and chemical composition on enamel demineralization and subsequent remineralization

Alkattan

Lippert

Tang

et al. 2018

Journal of Dentistry

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“…e oral cavity forms a unique ecological niche for micro-organisms, most of which accumulate on dental surfaces to form dental plaque (oral biofilm). Cariogenic bacteria that can ferment carbohydrates to produce acid and further demineralize the tooth surfaces are the primary aetiologic agents of dental caries [3][4][5]. Streptococcus mutans, lactobacilli, Actinomyces spp.…”

Section: Introductionmentioning

confidence: 99%

Application of Antibiotics/Antimicrobial Agents on Dental Caries

Qiu

Zhou

et al. 2020

BioMed Research International

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Dental caries is the most common oral disease. The bacteriological aetiology of dental caries promotes the use of antibiotics or antimicrobial agents to prevent this type of oral infectious disease. Antibiotics have been developed for more than 80 years since Fleming discovered penicillin in 1928, and systemic antibiotics have been used to treat dental caries for a long time. However, new types of antimicrobial agents have been developed to fight against dental caries. The purpose of this review is to focus on the application of systemic antibiotics and other antimicrobial agents with respect to their clinical use to date, including the history of their development, and their side effects, uses, structure types, and molecular mechanisms to promote a better understanding of the importance of microbial interactions in dental plaque and combinational treatments.

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“…The chemoparasitic caries theory states that bacteria inhabit the mouth and produce acids that dissolve tooth structures in the presence of fermentable carbohydrates [7]. Cariogenic bacteria that can ferment carbohydrates to produce acid and further demineralize the tooth surfaces are the primary etiologic agents of dental caries [8][9][10]. The oral cavity is a unique ecological niche of microorganisms, most of which accumulate on dental surfaces to form dental plaque (oral biofi lm) [11] and thus, bacteria (dental plaque) are considered the primary factor among caries aetiologic factors.…”

Section: Introductionmentioning

confidence: 99%

Susceptibility Pattern of Bacterial Isolates from Dental Caries Patients Attending Clinic at Irrua Specialist Teaching Hospital, Irrua, Nigeria

Philips¹,

Timothy²,

Charlse³

et al. 2021

J Biomed Res Environ Sci

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This study was carried out to evaluate the antibiotic susceptibility pattern of bacterial isolates from dental caries patients attending the clinic at Irrua Specialist Teaching Hospital, Irrua, Nigeria. A total of 223 bacteria samples (Streptococcus mutans = 151; Streptococcus sobrinus = 36; Lactobacillus acidophilus = 22; Streptococcus salivarius = 10; Streptococcus mitis = 4) were collected from the patients. Antimicrobial sensitivity testing was done by single disc agar diffusion method on 24 antibiotics; selected into eight different groups of 3 according to action, community usage, and generation. The average group susceptibility of antibiotics to all bacterial isolates were 25.71%, 53.81%, 13.75%, 32.74%, 10.76%, 8.52%, 0.60% and 64.42% for group 1 to 8 respectively. Specifically, the most potent antibiotic in the different groups of antibiotics was Amoxicillin (42.60%), Unasyn (78.03%), Chloramphenicol (37.67%), Erythromycin (74.44%), Streptomycin (28.70%), Cefotaxime (18.39%), Pefloxacin (1.79%) and Clindamycin (96.41%). There was total resistance of all isolates to Cotrimoxazole, Neomycin, Ciprofloxacin, and Ofloxacin. The overall sensitivity of each isolated bacterial to the 24 antibiotics was 26.27%, 26.62%, 22.73%, 32.50%, and 28.13% for Strep. mutans, Strep. sobrinus, L. acidophilus, Strep. salivarius and Strep. mitis respectively. Considering the overall low sensitivity of dental caries isolates to the overall 24 antibiotics, there is a need for antibiotic susceptibility screening before an antibiotic prescription for the treatment of dental caries.

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The effects of lesion baseline characteristics and different Sr:Ca ratios in plaque fluid-like solutions on caries lesion de- and remineralization

Cited by 7 publications

References 40 publications

The influence of hardness and chemical composition on enamel demineralization and subsequent remineralization

The influence of hardness and chemical composition on enamel demineralization and subsequent remineralization

Application of Antibiotics/Antimicrobial Agents on Dental Caries

Susceptibility Pattern of Bacterial Isolates from Dental Caries Patients Attending Clinic at Irrua Specialist Teaching Hospital, Irrua, Nigeria

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