The effects of KR-10876, a new quinolone antimicrobial agent, on the central nervous system

Kim, Eun Joo; Woo, Shin Sang; Shin, Hwa Sup; Roh, Jung Koo; Park, Myoung Whan; Kim, Wan Joo

doi:10.1007/bf02974120

Cited by 1 publication

(1 citation statement)

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“…Leucine, proline, and glycine are all important amino acids that play different roles in the human body. Leucine is essential for muscle protein synthesis and the maintenance of muscle mass, proline is important for the formation of collagen and the prevention of protein misfolding diseases, and glycine is involved in the synthesis of important molecules and the regulation of inflammation [ 68 , 69 , 70 ]. Three of these elements were enhanced in the AgNPs + P. indica treatment ( Table 4 ).…”

Section: Discussionmentioning

confidence: 99%

Chemically Synthesized AgNPs and Piriformospora indica Synergistically Augment Nutritional Quality in Black Rice

Solanki

Gupta

Kapoor

et al. 2023

JoF

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The use of biofertilizers has been the spotlight of research aiming to mitigate the food security threat as well as to restore the fertility of agricultural lands, for decades. Several studies are being conducted to unravel the role and mechanisms of plant growth-promoting microbes. In the present research, we evaluated the effect of silver nanoparticles (AgNPs) and Piriformospora indica on the growth and nutritional enhancement of black rice (Oryzae sativa. L.) individually and in combination. Among the different treatment conditions, the AgNPs + P. indica treatment led to a significant (p ≤ 0.05) increase in morphological and agronomic parameters. In comparison to the control, the percentage increase in plant height in AgNPs-treated black rice was 2.47%, while that for the treatment with only P. indica was 13.2% and that for the treatment with both AgNPs + P. indica was 30.9%. For the number of productive tillers, the effect of AgNPs in comparison to the control was non-significant; however, the effect of P. indica and AgNPs + P. indica showed a significant (p ≤ 0.05) increase of 13.2% and 30.9% in both the treatments, respectively. Gas chromatography mass spectrophotometry analysis of grains revealed that the contents of phenylalanine, tryptophan, and histidine (aromatic amino acids) were significantly (p ≤ 0.05) increased by 75%, 11.1%, and 50%, respectively, in P. indica-treated black rice. Nutrient profiling showed that macronutrients such as potassium, calcium, magnesium were found to be increased by 72.8%, 86.4% and 59.2%, respectively, in the treatment with AgNPs + P. indica in comparison to the control plants. Additionally, a significant (p ≤ 0.05) increase of 51.9% in anthocyanin content was observed in AgNPs + P. indica-treated black rice. The P. indica treatment also showed improved growth and augmented nutrient contents. From this study, we were able to understand that AgNPs + P. indica treatment would be a better plant growth-promoting factor and further evaluation would enable us to obtain a clear picture of its mechanisms of action.

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Section: Discussionmentioning

confidence: 99%