The Effects of Increased Intracranial Pressure Upon the Oxygenation of Blood in Dogs

Arterial oxygen tension and high intracranial pressure

“…In Berman's experimental series of dogs respirated with air, p02 dropped from 102 mmHg to 80 mmHg when intraeranial pressure was raised to levels below 100 mmHg, and to 68 mmHg when intracranial pressure was raised to levels above 100 mmHg (Berman et al 1969). In dogs breathing spontaneously arterial p02 dropped from 74 mmHg to 59 mmHg when intraeranial pressure was raised to a level between the systolic and diastolic blood pressure (Moss et al 1974).…”

Diffuse experimental brain injury: Methods, histological findings, and changes in intracranial pressure and blood pressure

“…Several different methods of raisingthe intracraniM pressure have been used (Berman et al 1969, Kaste 1970, Kuurne 1971, Langfitt et al 1964, Ommaya et al 1964. The results have differed considerably; for instance, with a local cold lesion the animals died at much lower levels of intracranial pressure than when iutraeranial pressure was raised hydrostatically (Kuurne and Troupp 1972).…”

Síndrome da reperfusão encefálica. Hipóteses fisiopatológicas, bioquímicas e hemodinâmicas do fenômeno da hipoperfusão pós-hiperemia

“…Ocorreu, assim, uma hipoperfusão pós-hiperemia. 2,4,[7][8][9][10][11]22,32,41,42,[48][49][50]71 Hipoperfusão pós-hiperemia sob o ponto de vista bioquímico: segunda hipótese No terceiro tipo de isquemia, conforme relatado na introdução deste texto, uma situação intermediária, o fenômeno da hipoperfusão pós-hiperemia, ocorre após isquemias moderadas.…”