The Effects of Heat Treated Lima Beans (Phaseolus lunatus) on Plasma Lipids in Hypercholesterolemic Rats

Oboh, H.A.; Omofoma, C.O.

doi:10.3923/pjn.2008.636.639

Cited by 22 publications

(15 citation statements)

References 13 publications

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“…The significance of fiber in human nutrition is its role in lowering blood cholesterol with the attendant benefit of reducing the risk of developing diabetes, hypertension, cancer and hyper-cholestroleamia (Singh et al, 2002;Koulshon et al, 2005;Oboh and Omofoma 2008).…”

Section: Chemical Composition Of Raw Materialsmentioning

confidence: 99%

Chemical and Technological Studies on Some Medicinal Plants

Khalil

Abou-Raya

Ibrahim

et al. 2015

Journal of Food and Dairy Sciences

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This study indicate the importance of some wild medicinal plants such as milk thistle seed and chicory seed. Therefore , chemical characteristies such as crude protein, ether extract, crude fiber, amino acids, fatty acids, vitamin C and minerals contents were determined. Also ,the antioxidative properties such as phenolic compounds and flavonoid compounds and scavenging activity on DPPH free radicals were also determined. Moreover ,the possibility to use these seeds in biscuit production, where the utilization of milk thistle seed flour and chicory seed flour as replacers of wheat flour at different levels (5, 10, and 15%) to prepare biscuits rich in protein and minerals, as well as organoleptic evaluation of prepared biscuits and firmness values were also investigated. Results indicated that milk thistle seed and chicory seed have high amount of protein, ether extract, crude fiber, minerals content, vitamin C, flavonoids, and phenolic compounds (antioxidants) which, could be used as alternative natural source for synthetic antioxidants in industry.. The major unsaturated fatty acids in milk thistle seed and chicory seed oil are oleic and linoleic. The essential and nonessential amino acids are more abundant in milk thistle seed and chicory seed protein. Sensory evaluation of the obtained products indicated that successful replacement was 10% of both seeds. So , it could be recommended to use the investigated plant seeds in biscuit production for its nutritional concept and antioxidative effects. For these reasons, we must take in consideration to cultivate these plants on a large scale to take their advantages of their therapeutic and nutritional. Milk thistle (S. marianum L. Gaertn.) is cultivated as a medicinal plant but it can also be a troublesome weed (Khan et al., 2009) Milk thistle is an annual or biennial plant belongs to the family Asteraceae (Compositae), the plant is native to Mediterranean area and now has spread to other warm and dry regions (Li et al., 2012). Now silybum marianum is one of the most medicinal plants, the plant has many common names such as, bull thistle, heal thistle, holy thistle, lady's thistle, pig leaves, royal thistle, snake milk, so thistle, St.Mary's thistle, Venus thistle, Marian thistle, Mary thistle, mild thistle, milk ipecac, our lady's thistle (Corchete, 2008). Seed flour is a primary by-product from seed oil production and is often discarded as waste, this flour may contain many health beneficial components such as natural antioxidant and protein (Parry et al., 2008). Silymarin content of milk thistle seed ranged from 4 to 6% based on dry weight (Khalil,2008). Silymarin is the most commonly used herbal product for chronic liver disease (Freedman et al., 2011). Abd Raboh, (2012) revealed that the seed of milk thistle contained high amounts of protein (27.54%), ether extract (29.68%) and crude fiber (29.95%) on dry weight basis, also the seed had antioxidant properties due to its content of phenolics, flavonoids, saponins, silymarin and ascorbic acid. Chicory (Cichorium i...

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Section: Chemical Composition Of Raw Materialsmentioning

confidence: 99%

Chemical and Technological Studies on Some Medicinal Plants

Khalil

Abou-Raya

Ibrahim

et al. 2015

Journal of Food and Dairy Sciences

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“…Lima beans (Phaseolus lunatus L.), which have a high dietary fiber and 18:3 content, are good for lowering blood sugar levels and reducing the risk of heart attack and diabetes (Korytnyk and Metzler 1963;Oboh and Omofoma 2008). Lima bean plants originated from tropical zone in the northern Andes (Serrano-Serrano et al 2010) and belong to a chilling-susceptible species.…”

Section: Introductionmentioning

confidence: 99%

Cloning and expression of three fatty acid desaturase genes from cold-sensitive lima bean (Phaseolus lunatus L.)

Zhang

Wang

et al. 2010

Biotechnol Lett

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The critical chilling temperature of cold-sensitive lima bean (Phaseolus lunatus L.) seedlings was determined to be approx. 8°C. The full-length cDNAs of PlSAD, PlFAD2, and PlFAD3 encoding three fatty acid desaturases were isolated from lima bean leaves. The PlSAD open reading frame (ORF) had 1,317 bp and a single intron of 601 bp, encoding a polypeptide of 438 amino acids that showing 86% homology with the plastidial stearoyl-acyl carrier protein desaturase in soybean. The PlFAD2 ORF contained 1,059 bp and was uninterrupted, encoding a polypeptide of 352 amino acids having 85% identity with the microsomal omega-6 desaturase GmFAD2-3 in soybean. PlFAD3 ORF had 1,116 bp and seven introns, encoding a polypeptide of 371 amino acids showing 91% homology with the microsomal omega-3 desaturase FAD3 in cowpea. PlSAD and PlFAD2 were expressed highly in leaves but poorly in roots and stems, while PlFAD3 was expressed in three tissues. All three genes were significantly induced in leaves by drought. PlSAD and PlFAD3 in leaves were down-regulated by high temperature and salinity, whereas PlFAD2 was up-regulated by the two stresses. The expression patterns of the three genes in lima bean leaves under suboptimal temperature, 18°C, were different from those under 8°C. The down-regulation of PlSAD transcript at chilling temperature might be an important factor contributing to chilling susceptibility for lima bean plants.

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“…They have many medicinal uses including, microbial, anti-tumor, anti-insect [4] hepatoprotective, haemolytic [5], and anti-inflammatory activities. They also decrees blood cholesterol level and may be used as adjuvant in vaccines [6][7][8][9][10][11][12]. In addition, saponins are used in preparation of soaps, detergents, fire extinguishers, shampoos, beer and cosmetic [13].…”

Section: Introductionmentioning

confidence: 99%

Saponin: Properties, Methods of Evaluation and Applications

Moghimipour

Handali

2015

ARRB

106

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Saponins are secondary metabolites with high molecular weight. They present in a wide range of plant species and are distributed throughout the bark, leaves, stems, roots and even flowers. Saponins are bitter in taste and in recent years, they have received considerable attention because of their various biological activities including hepatoprotective, anti-ulcer, anti-tumor, antimicrobial, adjuvant and anti-inflammatory activities. Saponins are composed of a lipid soluble aglycone consisting of either a sterol or more commonly a triterpenoid and water soluble sugar residues, due to their amphiphilic nature, they are highly surface active and their biological activities are related to their chemical structures. Both steroidal and triterpenoids saponins show detergent properties. The aim of the present article is to review the saponin and methods of evaluation and also, their application based on the recent studies.

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The Effects of Heat Treated Lima Beans (Phaseolus lunatus) on Plasma Lipids in Hypercholesterolemic Rats

Cited by 22 publications

References 13 publications

Chemical and Technological Studies on Some Medicinal Plants

Chemical and Technological Studies on Some Medicinal Plants

Cloning and expression of three fatty acid desaturase genes from cold-sensitive lima bean (Phaseolus lunatus L.)

Saponin: Properties, Methods of Evaluation and Applications

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