The Effects of Glomerular Filtration Rate on the Severity of Coronary Heart Disease

Ekici, Berkay; Tanındı, Aslı; Sayin, Irmak

doi:10.5543/tkda.2015.48323

Cited by 1 publication

(1 citation statement)

References 17 publications

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“…In addition, the presence of a negative correlation between eGFR levels and SYNTAX score in our study is consistent with similar studies in the literature. Ekici et al 31 investigated the relationship between eGFR and SYNTAX score in patients with stable coronary artery disease and found a significant negative correlation. Cay et al 32 investigated the relationship between coronary atherosclerosis and decreased renal function and found a significant association.…”

Section: Discussionmentioning

confidence: 99%

The Relationship between Acute-to-Chronic Glycemic Ratio and SYNTAX Score in Diabetic Patients Presenting with Acute Coronary Syndrome

Demir,

Balyimez

2023

Int J Angiol

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A new index called the acute-to-chronic (A/C) glycemic ratio has been proposed to better represent the true acute glycemic rise in people with acute disease. However, there has been no previous study investigating the relationship between A/C glycemic ratio and SYNTAX score in patients with diabetic acute coronary syndrome (ACS). The aim of this study is to evaluate the role of A/C glycemic ratio in predicting coronary artery disease severity and SYNTAX score in diabetic patients presenting with ACS. The study included 131 consecutive patients hospitalized for ACS in our hospital, previously diagnosed with diabetes and undergoing percutaneous coronary intervention. The relationship between A/C glycemic ratio and SYNTAX score calculated at the time of admission was determined in univariate and multivariate linear regression analyses. The sample size was divided into three parts (T1, T2, and T3) according to the admission blood glucose (ABG)/estimated average glucose (eAG) ratio. When ABG/eAG and SYNTAX scores were compared, there was no significant difference between the T1 and T2 groups, but a significant increase was found in the T3 group compared with the other two groups (T1: 14.26, T2: 14.77, T3: 24.41; p < 0.001). When multivariate modeling was performed with the two or three most relevant variables (age, estimated glomerular filtration rate [eGFR], and ABG/eAG ratio), the upper tertile of the ABG/eAG variable was correlated with the severity of coronary atherosclerosis and higher SYNTAX score. This study shows that there is a significant relationship between higher ABG/eAG ratio and higher SYNTAX score in diabetic patients presenting with ACS.

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Section: Discussionmentioning

confidence: 99%