The Effects of Fatigue and Pain on Daily Life Activities in Systemic Lupus Erythematosus

Özel, Filiz; Argon, Gülümser

doi:10.5505/agri.2015.38278

Cited by 9 publications

(10 citation statements)

References 23 publications

(33 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other aspects related to pain in SLE patients seen in this study are flexibility and strength. In SLE patients, bodily pain may be associated with primary fibromyalgia, 37 muscle fatigue, 38 and/or changes in physical and mental aspects, 39,40 so the improvements in flexibility and strength in the kinesiotherapy group probably influenced not only pain reduction, but also the other aspects related to quality of life evaluated by the SF-36 test. The lack of significance of the improvements in the SF-36 scores and in the strength tests was due to the small number of patients in this study.…”

Section: Discussionmentioning

confidence: 99%

Increased flexibility, pain reduction and unaltered levels of IL-10 and CD11b + lymphocytes in patients with systemic lupus erythematosus were associated with kinesiotherapy

Timóteo

Silva

Micheli

et al. 2018

Lupus

View full text Add to dashboard Cite

The effect of physical activity on the immune system is still poorly understood in cases of systemic lupus erythematosus (SLE). Therefore, our aim was to investigate differences in the serum levels of cytokines (IL-2, IL-5, IL-6, IL-8, IL-10 and TNF-α) and the numbers of CD11b + and CXCR2 + neutrophils and lymphocytes in women with SLE undergoing drug treatment, without ( n = 9) or with ( n = 5) 4 months of kinesiotherapy. Parameters related to functional capacity were also analyzed. In the case of the patients who were not submitted to kinesiotherapy, there were reductions in the levels of IL-5, IL-6 and IL-10, and an increase in the number of CD11b + leukocytes, in addition to an increase in abdominal circumference after the monitoring time. Patients submitted to kinesiotherapy did not present changes in serum cytokines or in the numbers of CD11b + and CXCR2 + neutrophils and lymphocytes, but there were increases of flexibility and strength, as well as a reduction in pain sensation after the monitoring time. In conclusion, kinesiotherapy was able to increase flexibility and reduce pain in SLE patients without influencing immune parameters.

show abstract

Section: Discussionmentioning

confidence: 99%

Increased flexibility, pain reduction and unaltered levels of IL-10 and CD11b + lymphocytes in patients with systemic lupus erythematosus were associated with kinesiotherapy

Timóteo

Silva

Micheli

et al. 2018

Lupus

View full text Add to dashboard Cite

show abstract

“…The most common symptom of SLE is fatigue, with about 51%~ 90% of SLE patients experiencing fatigue problem [9]. Fatigue can affect the daily lives of SLE patients [10, 11], and is also related to sleep disorders [12], pain, depression, and quality of life [13]. Fatigue is a subjective phenomenon without clinically validated definition [14], and it’s hard for patients with fatigue problem to participate in a long time investigation, so a reliable and simple instrument to measure fatigue problem of SLE is important, which would be conducive to interventions and outcomes monitoring.…”

Section: Introductionmentioning

confidence: 99%

Psychometric properties of fatigue severity scale in Chinese systemic lupus erythematosus patients

Feng

Yan

et al. 2019

Health Qual Life Outcomes

View full text Add to dashboard Cite

Background Fatigue is the most common symptom in Systemic Lupus Erythematosus (SLE) patients. Many fatigue instruments have been used in SLE, with Fatigue Severity Scale (FSS) mostly adopted. However, fatigue instruments haven’t been tested in the Chinese SLE population. The aim of our study was to test the psychometric properties of FSS in Chinese SLE patients. Methods A cross-sectional study was conducted. 201 patients diagnosed with SLE were enrolled in the study with convenience sampling. Fatigue score, depression score and vitality subscale score of SF-36 were collected. Floor and ceiling effects were tested. Factor analysis was conducted. Reliability and validity of FSS were also tested. Results Floor (4.50%) and ceiling (4.00%) effects were minimal. One factor was extracted, explaining 61.80% of total variance. When item1 and item 2 were deleted, one factor explained 69.54% of variance, and Cronbach’s Alpha increased from 0.92 to 0.93. Intraclass correlation coefficient (ICC) was 0.94. Fatigue correlated with both depression ( r = 0.52, P < 0.01) and vitality ( r = − 0.55, P < 0.01), indicating acceptable construct validity for original FSS. When item 1 and 2 were removed, the correlation coefficient between 7-item FSS and vitality increased ( r = − 0.58, P < 0.01), while correlation coefficient between 7-item FSS and depression remained the same ( r = 0.52, P < 0.01). Known-groups validity was verified by that patients with depression showed higher fatigue score both for 9-item ( Z = -5.56, P < 0.001) and 7-item FSS ( Z = -5.70, P < 0.001). Conclusions 9-item FSS is a reliable instrument and can be used to assess fatigue problem in Chinese SLE patients, and 7-item FSS also demonstrated good psychometric properties in the same participants.

show abstract

“…Studies indicate that fatigue in SLE is associated with anxiety, depression, pain and body mass index (BMI). 8 , 9 The correlation between fatigue scoring and depression is higher in the SLE population than other medical conditions such as Lyme disease or multiple sclerosis. 10 , 11 Jump et al 12 find the importance of pain in predicting fatigue levels in SLE patients.…”

Section: Introductionmentioning

confidence: 99%

Fatigue of systemic lupus erythematosus in China: contributors and effects on the quality of life

Du¹,

Zhao²,

Zhuang³

et al. 2018

PPA

View full text Add to dashboard Cite

ObjectiveFatigue is a very common symptom of systemic lupus erythematosus (SLE), which significantly impairs patients’ quality of life. The purpose of this study is to evaluate contributors of fatigue and effects of fatigue on the quality of life in Chinese SLE patients.MethodsA survey of 119 SLE patients using the Fatigue Severity Scale (FSS) to assess the severity of fatigue was carried out. SLE patients completed the Systemic Lupus Erythematosus Disease Activity Index, the Hospital Anxiety and Depression Scale, the Short Form 36 health survey and the Pittsburgh Sleep Quality Index. Meanwhile, 105 healthy individuals completed FSS, the Hospital Anxiety and Depression Scale and Short Form 36 health survey. We used chi-squared analysis, independent samples t-tests and logistic regression models to analyze data.ResultsOur results found that the FSS score of patients with SLE was higher than that of healthy controls. The disease duration, anxiety, depression, subjective sleep quality and sleep disorders significantly correlated with fatigue in SLE patients. Moreover, logistic regression models showed depression and sleep disorders as predictors of fatigue. In SLE patients, fatigued patients had lower quality of life than those who were non-fatigued.ConclusionThis is the first time to explore contributors of fatigue and the influence of fatigue on SLE patients’ quality of life in China. Our study showed that depression and sleep disorders were predictors of fatigue, and fatigue seriously damaged SLE patients’ quality of life. The results indicate that it is necessary to conduct holistic assessment and effective intervention, such as systemic psychiatric screening, psychological care and practical sleep guidance, to relieve symptoms of fatigue and finally improve their quality of life in SLE patients.

show abstract

The Effects of Fatigue and Pain on Daily Life Activities in Systemic Lupus Erythematosus

Cited by 9 publications

References 23 publications

Increased flexibility, pain reduction and unaltered levels of IL-10 and CD11b + lymphocytes in patients with systemic lupus erythematosus were associated with kinesiotherapy

Increased flexibility, pain reduction and unaltered levels of IL-10 and CD11b + lymphocytes in patients with systemic lupus erythematosus were associated with kinesiotherapy

Psychometric properties of fatigue severity scale in Chinese systemic lupus erythematosus patients

Fatigue of systemic lupus erythematosus in China: contributors and effects on the quality of life

Contact Info

Product

Resources

About