The effects of exercise training on quality of life in HAART-treated HIV-positive Rwandan subjects with body fat redistribution

Mutimura, Eugene; Stewart, Aimée; Crowther, Nigel J.; Yarasheski, Kevin E.; Cade, W. Todd

doi:10.1007/s11136-008-9319-4

Cited by 94 publications

(181 citation statements)

References 45 publications

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“…After screening titles and application of the eligibility criteria, 21 studies (Baigis et al, 2002;Cade et al, 2003;Cade et al, 2013;Cutrono et al, 2015;Dolan et al, 2006;Ezema et al, 2014;Hand et al, 2008;Jaggers et al, 2014;MacArthur et al, 1993;Mangona et al, 2015;Mapstone et al, 2014;Mutimura et al, 2008;Neto et al, 2016;Oursler et al, 2009;Perna et al, 1999;Ramírez-Marrero et al, 2014;Raso et al, 2013;Smith et al, 2001;Sullivan et al, 2014;Terry et al, 2006;Thoni et al, 2002) were eligible for inclusion in the meta-analysis. (n=31) and sub-maximal (n=5) exercise tests.…”

Section: Search Results and Flow Of Studies Through The Reviewmentioning

confidence: 99%

Cardiorespiratory fitness levels and moderators in people with HIV: A systematic review and meta-analysis

Vancampfort

Mugisha

Rosenbaum

et al. 2016

Preventive Medicine

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Cardiorespiratory fitness (CRF) is a modifiable risk factor for cardiovascular disease and premature mortality. CRF levels and moderators among people living with HIV (PLWH) are unknown. The aim of the current meta-analysis was to (1) determine mean CRF in PLWH and compare levels with age-and gender-matched healthy controls (HCs), (2) explore moderators of CRF,3and (4) explore moderators of CRF outcomes following physical activity (PA) interventions. Major electronic databases were searched systematically for articles reporting CRF expressed as maximum or peak oxygen uptake (ml/min/kg) in PLWH. A random effects meta-analysis calculating the pooled mean CRF including subgroup-and meta-regression analyses was undertaken. Across 21 eligible studies, the CRF level was 26.4 ml/kg/min (95%CI=24.6 to 28.1) (n=1,010; mean age =41years). There were insufficient data to compare CRF levels with HCs. A higher body mass index (β=-0.99, 95%CI=-1.93 to -0.06, P=0.04), older age (β=-0.31, 95%CI=-0.58 to -0.04, P=0.02) and the presence of lipodystrophy (β=-4.63, 95%CI=-7.88 to -1.39, P=0.005) were significant moderators of lower CRF levels. Higher CD4+ counts (β=0.004, 95%CI=0.0007 to 0.007, P=0.016), supervised interventions (P<0.001) and interventions with a lower frequency of weekly sessions (2 or 3 versus 4 times) (P<0.001) predicted a better CRFoutcome following PA. CRF levels of PLWH are among the lowest in comparison to other vulnerable populations. More research on the most optimal physical activity intervention characteristics is needed.

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Section: Search Results and Flow Of Studies Through The Reviewmentioning

confidence: 99%

Cardiorespiratory fitness levels and moderators in people with HIV: A systematic review and meta-analysis

Vancampfort

Mugisha

Rosenbaum

et al. 2016

Preventive Medicine

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“…These effects are important in the light of HIV-associated diseases, including lipodystrophy, body changes, the side effects of antiretroviral medication and comorbidities. In addition, improvements in cardiopulmonary fitness and functional capacities have an important role in the management of daily life, wellbeing and quality of life of people living with HIV (Mutimura et al 2008, Myburgh and De Bruto 2008, Gomes et al 2013a). …”

Section: Introductionmentioning

confidence: 99%

Effects of an exercise programme with people living with HIV: research in a disadvantaged setting

Ley

Leach

Barrio

et al. 2014

African Journal of AIDS Research

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This study aimed to analyse the physical health effects of a community based 10-week physical activity programme with people living with HIV. It was developed, implemented and evaluated in a disadvantaged community in South Africa. A pre-post research design was chosen. Major recruitment and adherence challenges resulted in a small sample. Among the 23 participants who took part in both baseline and final testing, compliant participants (n = 12) were compared to non-compliant participants (n = 11). Immunological (CD4, viral load), anthropometric (height, weight, skinfolds and waist to hip ratio), muscular strength (h1RM) and cardiopulmonary fitness (time on treadmill) parameters were measured. The compliant and non-compliant groups were not different at baseline. Muscular strength was the parameter most influenced by compliance with the physical activity programme (F = 4.516, p = 0.047). Weight loss and improvement in cardiopulmonary fitness were restricted by the duration of the programme, compliance and influencing factors (e.g. nutrition, medication). The increase in strength is significant and meaningful in the context, as the participants' goals were to look healthy and strong to avoid HIV related stigma. The improvements in appearance were a motivational factor, especially since the changes were made visible in a short time. Practical implications for health promotion are described. More research contextualised in disadvantaged settings is needed.

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“…19 Participants randomized to 6 months of exercise training demonstrated improvements in metabolic outcomes, cardiorespiratory fitness, body composition, and quality of life relative to non-exercisers. 20 This is the first study to demonstrate the impact of exercise in a developing country.…”

Section: Evidence From the Literature: Interventions Exercisementioning

confidence: 98%

Evidence-Based Management of an Individual Living with HIV

O’Brien

Nixon²

2010

Physiotherapy Canada

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The effects of exercise training on quality of life in HAART-treated HIV-positive Rwandan subjects with body fat redistribution

Cited by 94 publications

References 45 publications

Cardiorespiratory fitness levels and moderators in people with HIV: A systematic review and meta-analysis

Cardiorespiratory fitness levels and moderators in people with HIV: A systematic review and meta-analysis

Effects of an exercise programme with people living with HIV: research in a disadvantaged setting

Evidence-Based Management of an Individual Living with HIV

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