The effects of epinephrine, as a supplement for epidural and spinal anesthesia, on the duration of analgesia during childbirth and Apgar Score: A systematic review and meta-analysis

Asgarlou, Zoleykha; Mohseni, Mohammad; Khosravizadeh, Omid; Ahmadi, Shiler; Sheyklo, Sepideh Gareh; Moosavi, Ahmad

doi:10.4103/nms.nms_56_18

Cited by 4 publications

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“…11 It can be classified as mild thrombocytopenia if the platelet count is between 100 × 10 9 /L to 150 × 10 9 /L, moderate if the platelet count is between 50 × 10 9 /L to 100 × 10 9 /L, and severe if the platelet count is less than 50 × 10 9 /L of blood. [12][13][14] During pregnancy, there is a general downward drop in platelet count specifically during the last trimester. The underlying mechanisms for the downward drift of platelet count might be through a combination of dilution effects, increased platelet consumption across the placenta, and mild immune process.…”

Section: Introductionmentioning

confidence: 99%

Magnitude and Associated Factors of Thrombocytopenia among Pregnant Women Attending Antenatal Care Clinics at Dessie Comprehensive Specialized Hospital, Northeast Ethiopia

Ebrahim

Kebede²,

Tilahun

et al. 2022

Clin Appl Thromb Hemost

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Background Thrombocytopenia is a common hematological abnormality during gestation. Pregnant women with severe thrombocytopenia may be associated with a higher risk of excessive bleeding during or after delivery. Therefore, the main aim of this study was to assess the magnitude and associated factors of thrombocytopenia among pregnant women attending antenatal care services at Dessie comprehensive and specialized hospital, Northeast Ethiopia. Methods An institution-based cross-sectional study was conducted from February to March 2021. Using a systematic random sampling technique, a total of 294 pregnant women were enrolled in the study. Structured interviewer-administered questionnaires were used to collect socio-demographic and clinical data of study participants. Four ml of venous blood were collected from each pregnant woman and a complete blood count was determined using DIRUI BF 6500 automated hematology analyzer. Data were entered into Epidata version 4.6.0 and then exported into SPSS version 24.0. Multivariate logistic regression was used to assess the association between dependent and independent variables. P-value < 0.05 was considered to be statistically significant. Results A total of 294 pregnant women who visited antenatal care services at Dessie comprehensive specialized hospital were included. The mean (±SD) age of the study participants was 29.7 (±6.1) years. The prevalence of thrombocytopenia among pregnant women was 9.9% (95% CI: 6.5, 13.6). A mild type of thrombocytopenia is the major type and accounted for 72.4% whereas moderate thrombocytopenia and severe thrombocytopenia accounted for 17.2% and 10.4% respectively among pregnant women. Multivariate logistic regression showed that urban residents (AOR: 0.206,95% CI, 0.055-0.748), gestational ages within the first trimester (AOR: 0.183, 95% CI, 0.057-0.593) and gestational ages within the second trimester (AOR = 0.264, 95% CI, 0.092-0.752) were significantly associated and independent predictors of thrombocytopenia in pregnant women. Conclusion In this study, the prevalence of thrombocytopenia was 9.9% and the mild type of thrombocytopenia (72.4%) was higher than the other type of thrombocytopenia among pregnant women. In multivariate logistic regression analysis, residence and gestational age (trimester) were significantly associated with thrombocytopenia. Therefore, the platelet count should be routinely determined during the antenatal care visit for proper diagnosis and to minimize bleeding during and or after childbirth.

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Section: Introductionmentioning

confidence: 99%

Magnitude and Associated Factors of Thrombocytopenia among Pregnant Women Attending Antenatal Care Clinics at Dessie Comprehensive Specialized Hospital, Northeast Ethiopia

Ebrahim

Kebede²,

Tilahun

et al. 2022

Clin Appl Thromb Hemost

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“…The rate of thrombocytopenia in pregnant women is 4 times greater than that in nonpregnant women. Therefore, timely diagnostic, preventive, and therapeutic measures are necessary for the effective management of thrombocytopenia during pregnancy [ 23 ]. Thrombocytopenia is the second most common hematologic disorder in the world and affects 7–10% of all pregnancies.…”

Section: Discussionmentioning

confidence: 99%

“…A systematic review and meta-analysis of global thrombocytopenia showed that the prevalence of thrombocytopenia is four times greater in pregnant women than in nonpregnant women [ 23 ]; the average global prevalence was 8.4% (CI: 6.9–10.1%) [ 23 ]. However, our study finding was higher than the global prevalence of thrombocytopenia.…”

Section: Discussionmentioning

confidence: 99%

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Magnitude of Thrombocytopenia and Associated Factors among Pregnant Women Attending the Antenatal Care Service Unit of Wachemo University Nigist Ellen Mohammed Comprehensive Specialized Hospital Hosanna, Southern Ethiopia

Tirago,

Yemane,

Tadasa

2024

Advances in Hematology

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Background. Thrombocytopenia is the second most common hematological disorder in pregnancy after anemia worldwide and affects 7-8% of all pregnancies. Pregnant women with thrombocytopenia have complications of excessive bleeding during or after childbirth, exudation at the cesarean section, and neonatal thrombocytopenia. Therefore, the main aim of this study was to assess the magnitude of thrombocytopenia and its associated factors among pregnant women attending the Antenatal Care Service Unit of Wachemo University Nigist Ellen Mohammed Comprehensive Specialized Hospital Hosanna, Southern Ethiopia. Materials and Methods. A cross-sectional study was conducted from June 1 to August 30, 2022, involving 209 consecutive pregnant women who came to the hospital during the study period for antenatal care follow-up. Sociodemographic, reproductive, and other clinical data were collected using a structured questionnaire. A four-milliliter venous blood specimen was collected for complete blood analysis and peripheral blood smear. The data were analyzed by using SPSS version 25. Descriptive statistical analysis and bivariate and multivariate logistic regression analyses were performed. A P value ≤0.05 was considered to indicate statistical significance. Results. The overall magnitude of thrombocytopenia among pregnant women was 14.8% (95% CI: 10, 19.6). The prevalence of mild, moderate, and severe thrombocytopenia was 77.4%, 16.1%, and 6.5%, respectively. Multivariate logistic regression revealed that rural residence (AOR = 2.6 and 95% CI = 1.02, 7.12), cigarette smoking (AOR = 8.4 and 95% CI = 1.86, 38), anemia (AOR = 8.3 and 95% CI = 2.7, 25.6), and alcohol consumption (AOR = 8.2 and 95% CI = 2.17–31) were significantly independent factors associated with the development of thrombocytopenia. Conclusion. The magnitude of thrombocytopenia in this study was 14.8%. Rural residence, cigarette smoking, alcohol consumption, and anemia were significantly associated with thrombocytopenia. Therefore, the platelet count should be routinely determined during antenatal care visits for proper diagnosis and to minimize bleeding during and/or after childbirth.

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Analysis of the Clinical Effect of Music Combined with Hypnosis on Labor Analgesia Based on Data Mining

Chen

Wang

et al. 2021

Journal of Healthcare Engineering

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The objective of this paper is to study the curative effect of music combined with hypnosis on labor pains during childbirth. Based on the algorithm of data mining, we randomly selected 100 women who delivered babies in obstetric units from October 2020 to June 2021, set the control group and the observation group, obtained the relevant clinical data through comparison, and analyzed the value of music combined with hypnotic analgesia midwifery in obstetrics. The results showed that the number of spontaneous delivery cases in the observation group was higher than that in the control group ( P < 0.05 ) and the delivery time in the observation group was better than that in the control group ( P < 0.05 ). It is proved that music combined with hypnosis can effectively improve the rate of natural childbirth and shorten the overall labor time, so as to guarantee the health of mother and child.

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The effects of epinephrine, as a supplement for epidural and spinal anesthesia, on the duration of analgesia during childbirth and Apgar Score: A systematic review and meta-analysis

Cited by 4 publications

References 0 publications

Magnitude and Associated Factors of Thrombocytopenia among Pregnant Women Attending Antenatal Care Clinics at Dessie Comprehensive Specialized Hospital, Northeast Ethiopia

Magnitude and Associated Factors of Thrombocytopenia among Pregnant Women Attending Antenatal Care Clinics at Dessie Comprehensive Specialized Hospital, Northeast Ethiopia

Magnitude of Thrombocytopenia and Associated Factors among Pregnant Women Attending the Antenatal Care Service Unit of Wachemo University Nigist Ellen Mohammed Comprehensive Specialized Hospital Hosanna, Southern Ethiopia

Analysis of the Clinical Effect of Music Combined with Hypnosis on Labor Analgesia Based on Data Mining

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