The Effects of Eating a Traditional High Fat or a Ketogenic Diet on Sensitivity of Female Rats to Morphine-Induced Antinociception, Tolerance and Withdrawal
Abstract:ID 27565 Poster Board 417Opioid drugs like morphine are used for pain relief but also have high abuse potential. Further, individuals diagnosed with obesity are at a greater risk for opioid overdose. While overconsumption of a high fat diet can lead to obesity, it is not known if diet impacts sensitivity of individuals to morphine. To explore this possibility, the effects of morphine under acute and chronic conditions, as well as non-precipitated withdrawal were assessed in 24 female Sprague Dawley rats (n=8/g… Show more
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