The effects of different aerobic exercise intensities on serum serotonin concentrations and their association with Stroop task performance: a randomized controlled trial

Zimmer, Philipp; Stritt, Christian; Bloch, Wilhelm; Schmidt, Frank-Peter; Hübner, Sven T.; Binnebößel, Stephan; Schenk, Alexander; Oberste, Max

doi:10.1007/s00421-016-3456-1

Cited by 61 publications

(37 citation statements)

References 43 publications

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“…It has been reported that during intensive acute exercise, serum serotonin levels increase when compared to controls. 11 Moreover, moderate exercise in horses (a 450-m run) causes both free plasma 5-HT and whole blood 5-HT to increase by greater than threefold. 12 The authors concluded that the source of 5-HT was enterochromaffin cells that are thought to release 5-HT in response to exercise.…”

Section: Discussionmentioning

confidence: 99%

Serum serotonin levels in patients with epileptic seizures

et al. 2018

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Profound cardiovascular and/or respiratory dysfunction is part of the terminal cascade in sudden unexpected death in epilepsy (SUDEP). Central control of ventilation is mediated by brainstem rhythm generators, which are influenced by a variety of inputs, many of which use the modulatory neurotransmitter serotonin to mediate important inputs for breathing. The aim of this study was to investigate epileptic seizure-induced changes in serum serotonin levels and whether there are potential implications for SUDEP. Forty-one epileptic patients were pooled into 2 groups based on seizure type as (1) generalized tonic-clonic seizures (GTCS) of genetic generalized epilepsy and focal to bilateral tonic-clonic seizures (FBTCS; n = 19) and (2) focal seizures (n = 26) based on clinical signs using surface video-electroencephalography. Postictal serotonin levels were statistically significantly higher after GTCS and FBTCS compared to interictal levels (P = .002) but not focal seizures (P = .941). The change in serotonin (postictal-interictal) was inversely associated with a shorter duration of tonic phase of generalized seizures. The interictal serotonin level was inversely associated with a shorter period of postictal generalized electroencephalographic suppression. These data suggest that peripheral serum serotonin levels may play a role in seizure features and earlier postseizure recovery; these findings merit further study.

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Section: Discussionmentioning

confidence: 99%

Serum serotonin levels in patients with epileptic seizures

et al. 2018

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“…For example, they provide ample evidence of specific effects of acute aerobic exercise on executive function (EF) and attention. Acute aerobic exercise is a one-session intervention, which may involve 25 min of treadmill or cycle exercise at a target heart rate of 60% of the heart rate reserve (Bullock & Giesbrecht, 2014;Dunsky et al, 2017;Netz et al, 2016;Tine, 2014;Zimmer et al, 2016). Importantly, acute aerobic exercise differs from acute resistance exercise in the immediate acute physiological responses, as well as in the long-term physiological adaptations (Knuttgen, 2007).…”

Section: Introductionmentioning

confidence: 99%

The Acute Effect of Exercise on Executive Function and Attention: Resistance Versus Aerobic Exercise

Tsuk¹,

Netz²,

Dunsky³

et al. 2019

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“…One possible explanation for the efficacy of physical exercise in depression is linked to its biological correlates: In fact, in healthy adults, acute exercise determines an increase in serotonin serum levels which are altered in depression . Additionally, as suggested by animal models, physical exercise may promote synaptic plasticity in the hippocampus through the brain‐derived neurotrophic factor (BDNF) .…”

Section: Introductionmentioning

confidence: 99%