The Effects of Curcumin Gel Against Tannerella Forsythia (Clinical and Microbiological study)

Abstract

Aim of the study: To determine the effects of curcumin gel on Tannerella forsythia.
 Materials and methods: Eleven individuals were chosen with probing pocket depths of more than or equal to 5 mm. Scaling and root planing (SRP) were done on entire mouth, then curcumin and placebo gel were applied. At baseline and third visit (after one month), bleeding on probing (BOP), probing pocket depth (PPD), and relative attachment levels (RAL) were measured with a collection of subgingival plaque. The real-time polymerase chain reaction method has been used for bacterial analysis.
 Results: There was a substantial lessening in the bacterial outcomes, PPD and RAL when comparing the curcumin with the placebo group, while the difference was not significant with respect to BOP. On intra-group comparison, only the test group showed a significant decrease in bacterial count, BOP, and RAL, while both groups showed a significant reduction in PPD.
 Conclusion: Curcumin gel has an antimicrobial impact on T.Forsythia and a significant effect on improving BOP, PPD, and RAL.