Sleep and Control of Breathing 2018
DOI: 10.1183/13993003.congress-2018.oa3289
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The effects of CPAP-withdrawal on cerebral vascular reactivity and brain oxygenation in patients with obstructive sleep apnoea: a randomised-controlled trial.

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“…Following with the mechanisms linking IH to cardiovascular disease, T hiel et al . [4] explored the impaired cerebral vascular reactivity in response to 14 nights of CPAP withdrawal compared to continuation of real CPAP in moderate to severe OSA patients. Although there was a significant increase in blood pressure upon CPAP withdrawal and a full recurrence of sleep disordered breathing, there was no significant effect of CPAP withdrawal on cerebral vascular reactivity (CVR) assessed via blood oxygen level-dependent magnetic resonance imaging (MRI).…”
Section: Pathophysiological Aspects Of Sleep Disordered Breathing: Inmentioning
confidence: 99%
“…Following with the mechanisms linking IH to cardiovascular disease, T hiel et al . [4] explored the impaired cerebral vascular reactivity in response to 14 nights of CPAP withdrawal compared to continuation of real CPAP in moderate to severe OSA patients. Although there was a significant increase in blood pressure upon CPAP withdrawal and a full recurrence of sleep disordered breathing, there was no significant effect of CPAP withdrawal on cerebral vascular reactivity (CVR) assessed via blood oxygen level-dependent magnetic resonance imaging (MRI).…”
Section: Pathophysiological Aspects Of Sleep Disordered Breathing: Inmentioning
confidence: 99%