“…Perhaps one of the most striking potential features of contact with nature, and sharing some commonality with other ‘lifestyle’ factors, are the seemingly pleiotropic beneficial health effects it may have on general health ( Cox et al, 2017 ), including but not limited to improved birth outcomes ( Dzhambov et al, 2014 ; Twohig-Bennett and Jones, 2018 ), asthma and allergies ( Cavaleiro Rufo et al, 2021 ), improved immune functioning ( Li et al, 2008 ; Li and Kawada, 2011 ; Hall and Knuth, 2019 ), diabetes ( Brown et al, 2016 ; Thiering et al, 2016 ; Tsai et al, 2021 ), lowering blood pressure ( Shanahan et al, 2016 ), reduction in pain perception acutely ( Lechtzin et al, 2010 ) and chronically ( Wells et al, 2019 ), improving postoperative recovery ( Park and Mattson, 2009 ) and reduced mortality ( James et al, 2016 ; Crouse et al, 2017 ). Furthermore, there is evidence to suggest beneficial effects on a number of possible mechanisms of action implicated in the aetiology and pathophysiology of depression, including reducing stress ( Yao et al, 2021 ), inflammation ( Stier-Jarmer et al, 2021 ) and obesity ( Schalkwijk et al, 2018 ), improving wellbeing ( Martin et al, 2020 ; Pritchard et al, 2020 ; Pirchio et al, 2021 ) and improved sleep ( Shin et al, 2020 ). Coupled with the emerging literature that provides promising evidence suggesting a benefit for depression ( Hossain et al, 2020 ; Olafsdottir et al, 2020 ; Williams et al, 2020 ; Antonelli et al, 2021 ; Rosa et al, 2021 ; Stier-Jarmer et al, 2021 ), NBIs appear to be a viable strategy to pursue in mitigating the personal, social and societal burden of depression.…”