The effects of childhood emotional maltreatment and alexithymia on depressive and manic symptoms and suicidal ideation in females with bipolar disorder: emotion dysregulation as a mediator

Khosravani, Vahid; Berk, Michael; Bastan, Farangis Sharifi; Ardestani, Seyed Mehdi Samimi; Wrobel, Anna L

doi:10.1080/13651501.2021.1879867

Cited by 19 publications

(11 citation statements)

References 123 publications

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“…In addition to the contribution of ED to the functional impairment associated with adult ADHD, our results suggest a weak, albeit signi cant contribution of childhood maltreatment to ED and sleep problems. This is consistent with a number of studies suggesting that environmental factors and especially childhood maltreatment are involved in the development and the severity of ED in ADHD (54), similar to other disorders, such as BPD and BD (54,99,100).…”

Section: Multiple Linear Regression Analysessupporting

confidence: 92%

Identifying different patterns of emotional dysregulation in adult ADHD

Martz

Weiner

Weibel

2023

Preprint

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Background: Emotional dysregulation (ED) is a core intrinsic feature of adult presenting Attention Deficit Hyperactivity Disorder (ADHD). However, the clinical expressions of ED are diverse and several questionnaires have been used to measure ED in adults with ADHD. Thus, to date, the characteristics of ED in adult ADHD remain poorly defined. The objective of this study is to identify the different patterns of ED in adults with ADHD. Methods: A large sample of 460 newly diagnosed adults with ADHD were recruited. Patients completed a total of 20 self-reported questionnaires. Measures consisted in the several facets of ED, but also other clinical features of adult ADHD such as racing thoughts. A factor analysis with the principal component extraction method was performed to define the symptomatic clusters. A mono-dimensional clustering was then conducted to assess whether participants presented or not with each symptomatic cluster. Results: The factor analysis yielded a 5 factor-solution, including “emotional instability”, “impulsivity”, “overactivation”, “inattention/disorganization”, “sleep problems”. ED was part of two out five clusters and concerned 67.52% of our sample. Among those patients, the combined ADHD presentation was the most prevalent. Emotional instability and impulsivity were significantly predicted by childhood maltreatment. The ED and the “sleep problems” factors contributed significantly to the patients’ functional impairment. Conclusions: ED in ADHD is characterized along emotional instability and emotional impulsivity and significantly contribute to the functional impairment. However, beyond impairing symptoms, adult ADHD may also be characterized by functional strengths such as creativity.

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Section: Multiple Linear Regression Analysessupporting

confidence: 92%

Identifying different patterns of emotional dysregulation in adult ADHD

Martz

Weiner

Weibel

2023

Preprint

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“…Finally, one additional study 67 was identified by reviewing the references of included papers, resulting in 14 studies included in the qualitative synthesis, 10 of which [54][55][56][57]59,60,[62][63][64][65]67 were included in the quantitative synthesis. Four studies 56,57,62,68 did not provide data for the quantitative synthesis in the main text, but the correlations were provided after contacting the corresponding authors. Overall, the studies included in the MA provided 84 unique correlations between measures of ED and depressive symptoms and 82 univocal correlations between measures of ED and (hypo)manic symptoms.…”

Section: Study Characteristicsmentioning

confidence: 99%

Correlation between emotion dysregulation and mood symptoms of bipolar disorder: A systematic review and meta‐analysis

Oliva,

De Prisco,

Fico

et al. 2023

Acta Psychiatr Scand

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BackgroundEmotion dysregulation (ED) is a transdiagnostic construct characterized by difficulties regulating intense emotions. People with bipolar disorder (BD) are more likely to show ED and use maladaptive emotion regulation strategies than adaptive ones. However, little is known about whether ED in BD is a trait or it is rather an epiphenomenon of mood symptoms.MethodsWe conducted a systematic review and meta‐analysis of the evidence across major literature databases reporting correlations between measures of emotion regulation (overall ED and different emotion regulation strategies) and measures of depressive and (hypo)manic symptoms in BD from inception until April 12th, 2022.ResultsFourteen studies involving 1371 individuals with BD were included in the qualitative synthesis, of which 11 reported quantitative information and were included in the meta‐analysis. ED and maladaptive strategies were significantly higher during periods with more severe mood symptoms, especially depressive ones, while adaptive strategies were lower.ConclusionED significantly correlates with BD symptomatology, and it mainly occurs during mood alterations. ED may be a target for specific psychotherapeutic and pharmacological treatments, according to precision psychiatry. However, further studies are needed, including patients with mood episodes and longitudinal design, to provide more robust evidence and explore the causal direction of the associations.

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“…Although several studies have reported the relationship between childhood maltreatment and suicidality in various psychiatric disorders (Khosravani et al, in press; Mohammadzadeh, Ganji, et al, 2019), research in this regard on OCD patients is limited (e.g., Khosravani, Kamali, et al, 2017; Rukiye & Erbay, 2018). Exposure to childhood maltreatment may have negative impacts on treatment (Gershuny et al, 2008) and treatment‐seeking behaviours such as psychiatric care and medication use, independent of OCD‐related clinical factors such as OC severity and duration of illness in OCD patients (Benedetti et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

The effect of childhood maltreatment on suicidal ideation through cognitive emotion regulation strategies and specific obsessive–compulsive symptoms in obsessive–compulsive disorder

Khamesi

Najafi

Khosravani

2021

Clin Psychology and Psychoth

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Childhood maltreatment is thought to be associated with suicidality in patients with obsessive-compulsive disorder (OCD). Although the underlying mechanism of this relationship is not clear, cognitive emotion regulation strategies (CERSs) and the specific OC symptoms including unacceptable obsessional thoughts (UOTs) and responsibility for harm (RFH) may underlie this link. Accordingly, the study aimed to assess the effect of childhood maltreatment on suicidal ideation through UOTs, RFH and adaptive and maladaptive CERSs in OCD patients. Three hundred patients meeting a DSM-5 diagnosis of OCD were selected and completed the scales measuring childhood maltreatment, OCD, suicidality and depressive symptoms. After controlling for depressive symptoms and OCD severity, childhood maltreatment was shown to affect suicidal ideation directly. Also, the indirect effect of childhood maltreatment on suicidal ideation was mediated by adaptive CERSs, UOTs and RFH.The findings show that OCD patients with a history of childhood maltreatment, less use of adaptive CERSs and the experiences of UOTs and RFH should be carefully considered regarding suicidal risk.

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The effects of childhood emotional maltreatment and alexithymia on depressive and manic symptoms and suicidal ideation in females with bipolar disorder: emotion dysregulation as a mediator

Cited by 19 publications

References 123 publications

Identifying different patterns of emotional dysregulation in adult ADHD

Identifying different patterns of emotional dysregulation in adult ADHD

Correlation between emotion dysregulation and mood symptoms of bipolar disorder: A systematic review and meta‐analysis

The effect of childhood maltreatment on suicidal ideation through cognitive emotion regulation strategies and specific obsessive–compulsive symptoms in obsessive–compulsive disorder

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