The effects of caffeine on ambulatory blood pressure, heart rate, and mood in coffee drinkers

Green, Peter J.; Suls, Jerry

doi:10.1007/bf01857602

Cited by 73 publications

(32 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Caffeine has been classically regarded as an inducer of anxiety at higher doses, typically over 300 mg [10,24,27,28], but the consumption of caffeine is poorly correlated with anxiety or anxiety traits [17,29,30]. Besides dosage, the anxiogenic effect of caffeine is influenced by individual factors, such as preference for caffeine, presence of some anxiety disorders, and genetic background.…”

Section: S241mentioning

confidence: 99%

Caffeine, Mental Health, and Psychiatric Disorders

Lara

2010

JAD

181

127

View full text Add to dashboard Cite

Abstract. Caffeine intake is so common that its pharmacological effects on the mind are undervalued. Since it is so readily available, individuals can adjust their own dose, time of administration and dose intervals of caffeine, according to the perceived benefits and side effects of each dose. This review focuses on human studies of caffeine in subjects with and without psychiatric disorders. Besides the possibility of mild drug dependence, caffeine may bring benefits that contribute to its widespread use. These benefits seem to be related to adaptation of mental energy to the context by increasing alertness, attention, and cognitive function (more evident in longer or more difficult tasks or situations of low arousal) and by elevating mood. Accordingly, moderate caffeine intake (< 6 cups/day) has been associated with less depressive symptoms, fewer cognitive failures, and lower risk of suicide. However, its putative therapeutic effects on depression and ADHD have been insufficiently studied. Conversely, in rare cases high doses of caffeine can induce psychotic and manic symptoms, and more commonly, anxiety. Patients with panic disorder and performance social anxiety disorder seem to be particularly sensitive to the anxiogenic effects of caffeine, whereas preliminary data suggests that it may be effective for some patients with obsessive compulsive disorder (OCD). The threshold for the anxiogenic effect of caffeine is influenced by a polymorphism of the A2A receptor. In summary, caffeine can be regarded as a pharmacological tool to increase energy and effortful behavior in daily activities. More populational (cross-sectional and prospective) and experimental studies are necessary to establish the role of caffeine intake in psychiatric disorders, especially its putative efficacy on depressive mood and cognitive/attentional disorders.

show abstract

Section: S241mentioning

confidence: 99%

Caffeine, Mental Health, and Psychiatric Disorders

Lara

2010

JAD

181

127

View full text Add to dashboard Cite

show abstract

“…Daytime ambulatory blood pressure has generally been higher on caffeine days than on caffeine-free days (Jeong & Dimsdale 1990;James 1994;Superko et al, 1994;Green & Suls, 1996;Lane et al, 1998;Rakic et al, 1999), whereas some studies which reported ambulatory blood pressure recordings as 24 h means have failed to detect this pressor effect (MacDonald et al, 1991;Eggertsen et al, 1993) (Table 4).…”

Section: Acute Intake Of Coffee or Caffeine And Blood Pressurementioning

confidence: 99%

“…The pressor response has been reported as diminishing within a few days of the start of regular intake of caffeine (Robertson et al, 1981(Robertson et al, , 1984Ammon et al, 1983;Myers & Reeves, 1991). However, the tolerance may be partial, because in some studies caffeine was still able to elevate blood pressure during habitual consumption (Burr et al, 1989;Jeong & Dimsdale 1990;James 1994;Green & Suls, 1996). The pressor response to caffeine may be regained after a relatively short period of abstinence.…”

Section: Acute Intake Of Coffee or Caffeine And Blood Pressurementioning

confidence: 99%

Coffee, caffeine and blood pressure: a critical review

et al. 1999

View full text Add to dashboard Cite

Objective: We review the published data relating to intake of coffee and caffeine on blood pressure in man. We also refer to studies on the possible mechanisms of actions of these effects of caffeine. Design: The MEDLINE and Current Contents databases were searched from 1966 to April 1999 using the text words`coffee or caffeine' and`blood pressure or hypertension'. Controlled clinical and epidemiologic studies on the blood pressure effects of coffee or caffeine are reviewed. We also refer to studies on the possible mechanisms of action of these effects of caffeine. Results: Acute intake of coffee and caffeine increases blood pressure. Caffeine is probably the main active component in coffee. The pressor response is strongest in hypertensive subjects. Some studies with repeated administration of caffeine showed a persistent pressor effect, whereas in others chronic caffeine ingestion did not increase blood pressure. Epidemiologic studies have produced contradictory ®ndings regarding the association between blood pressure and coffee consumption. During regular use tolerance to the cardiovascular responses develops in some people, and therefore no systematic elevation of blood pressure in long-term and in population studies can be shown. Conclusions:We conclude that regular coffee may be harmful to some hypertension-prone subjects. The hemodynamic effects of chronic coffee and caffeine consumption have not been suf®ciently studied. The possible mechanisms of the cardiovascular effects of caffeine include the blocking of adenosine receptors and the inhibition of phosphodiesterases.

show abstract

“…Caffeine enhances physiological arousal, by activating both the sympathetic nervous system by increasing heart rate and blood pressure (Davidson and Smith 1991;Green and Suls 1996;James and Gregg 2004) and the hypothalamic pituitary adrenal axis by increasing cortisol (Lovallo et al 1996(Lovallo et al , 2005. Caffeine exerts physiological effects similar to those of acute stress (Gerra et al 2001;Kudielka et al 2004) and may augment the physiological stress response (Lovallo et al 2006).…”

Section: Introductionmentioning

confidence: 99%

Caffeine and theanine exert opposite effects on attention under emotional arousal

Giles

Mahoney

Brunyé

et al. 2017

Can. J. Physiol. Pharmacol.

View full text Add to dashboard Cite

Tea is perceived as more relaxing than coffee, even though both contain caffeine. L-theanine in tea may account for the difference. Consumed together, caffeine and theanine exert similar cognitive effects to that of caffeine alone, but exert opposite effects on arousal, in that caffeine accentuates and theanine mitigates physiological and felt stress responses. We evaluated whether caffeine and theanine influenced cognition under emotional arousal. Using a double-blind, repeatedmeasures design, 36 participants received 4 treatments (200 mg caffeine + 0 mg theanine, 0 mg caffeine + 200 mg theanine, 200 mg caffeine + 200 mg theanine, 0 mg caffeine + 0 mg theanine) on separate days. Emotional arousal was induced by highly arousing negative film clips and pictures. Mood, salivary cortisol, and visual attention were evaluated. Caffeine accentuated global processing of visual attention on the hierarchical shape task (p < 0.05), theanine accentuated local processing (p < 0.05), and the combination did not differ from placebo. Caffeine reduced flanker conflict difference scores on the Attention Network Test (p < 0.05), theanine increased difference scores (p < 0.05), and the combination did not differ from placebo. Thus, under emotional arousal, caffeine and theanine exert opposite effects on certain attentional processes, but when consumed together, they counteract the effects of each other.Key words: caffeine, theanine, arousal, attention, cortisol, emotion, cognition.Résumé : Le thé est perçu comme étant plus relaxant que le café, même si tous deux contiennent de la caféine. La L-théanine du thé pourrait être à l'origine de la différence entre les deux. Consommées ensemble, la caféine et la théanine exercent des effets similaires sur les facultés cognitives que la caféine seule, mais elles exercent des effets contraires sur l'éveil : effets d'accentuation de la caféine et effets mitigés de la théanine sur le plan des réactions au stress de natures physiologique et des sensations. Nous avons tenté de vérifier l'hypothèse selon laquelle la caféine et la théanine pourraient influencer les facultés cognitives en situation d'excitation émotionnelle. À l'aide d'un modèle à double insu avec mesures répétées sur des jours distincts, nous avons administré les traitements suivants chez 36 participants : caféine à 200 mg + théanine à 0 mg, caféine à 0 mg + théanine à 200 mg, caféine à 200 mg + théanine à 200 mg et caféine à 0 mg + théanine à 0 mg. Nous avons provoqué une excitation émotionnelle à l'aide d'images et de séquences filmées négatives. Nous avons évalué l'humeur, les taux de cortisol dans la salive et l'attention visuelle. La caféine entraînait une accentuation du traitement global par l'attention visuelle aux tâches de catégorisation de formes (« hierarchical shape task »; p < 0,05), la théanine entraînait une accentuation du traitement local (p < 0,05), et l'association des deux donnait les mêmes résultats que le placebo. La caféine entraînait une réduction des scores de différence des conflits en présenc...

show abstract

The effects of caffeine on ambulatory blood pressure, heart rate, and mood in coffee drinkers

Cited by 73 publications

References 47 publications

Caffeine, Mental Health, and Psychiatric Disorders

Caffeine, Mental Health, and Psychiatric Disorders

Coffee, caffeine and blood pressure: a critical review

Caffeine and theanine exert opposite effects on attention under emotional arousal

Contact Info

Product

Resources

About