The effects of breast milk storage and freezing procedure on interleukine-10 levels and total antioxidant activity

Aksu, Tekin; Atalay, Yıldız; Türkyılmaz, Canan; Gülbahar, Özlem; Hırfanoğlu, İbrahim Murat; Demirel, Nihal; Önal, Esra; Ergenekon, Ebru; Koç, Esin

doi:10.3109/14767058.2014.968844

Cited by 15 publications

(13 citation statements)

References 21 publications

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“…Storage at 4–6°C (39–43°F) for 48 hours did not result in a reduction in bactericidal capacity . When it was extended to 72 hours, bactericidal capacity and total anti‐oxidant capacity were halved . An upper limit of 72 hours has been proposed by the Academy of Breastfeeding medicine for home use for full‐term infants .…”

Section: Resultsmentioning

confidence: 99%

Review concludes that specific recommendations are needed to harmonise the provision of fresh mother's milk to their preterm infants

Buffin

Gremmo-Féger

et al. 2018

Acta Paediatrica

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AimThere are no specific recommendations for using a mother's fresh milk for her preterm infant. We reviewed the available evidence on its collection, storage and administration.MethodsThe working group of the French Neonatal Society on fresh human milk use in preterm infants searched the MEDLINE database and Cochrane Library up to June 2017 for papers published in English or French. They specifically analysed 282 papers providing information on prospective, retrospective and clinical studies and examined guidelines from various countries.ResultsThe review concluded that fresh mother's own milk should be favoured in accordance with the latest recommendations. However, it must be carried out under stringent conditions so that the expected benefits are not offset by risks related to different practices. The working group has summarised the best conditions for feeding preterm infants with human milk, balancing high nutritional and immunological quality with adequate virological and bacteriological safety. Professionals must provide parents with the necessary conditions to establish breastfeeding, together with specific and strong support.ConclusionBased on their review, the working group has made specific recommendations for using fresh mother's own milk under careful conditions, so that the expected benefits are not offset by risks related to practices.

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Section: Resultsmentioning

confidence: 99%

Review concludes that specific recommendations are needed to harmonise the provision of fresh mother's milk to their preterm infants

Buffin

Gremmo-Féger

et al. 2018

Acta Paediatrica

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“…7,19 It has been shown that the oxidative properties of breast milk change during long-term freezing and storage. 7,20 The present study evaluated antioxidant, oxidant and paraoxonase levels in transitional fresh breast milk collected between days 10 and 15 and stored at -20°C and -80°C for 72 hours and so changes that occurred during short-time freezing could also be evaluated. The level of antioxidants in fresh breast milk was shown to be significantly decreased after freezing and storage for 72 hours (p<0.05).…”

Section: Discussionmentioning

confidence: 99%

“…These changes can be demonstrated by the measurement of total antioxidant capacity (TAC), total oxidant status (TOS) and level of PON-1. [5][6][7] Paraoxonase-1 (PON-1), a sensitive and specific endogenous antioxidant enzyme, is produced in hepatocytes in the liver. Local chromatin paraoxonase (PON) in region q21-22 of chromosome 7 consists of three members called PON-1, PON-2 and PON-3.…”

mentioning

confidence: 99%

Effects of the storage of breast milk at different temperatures on total antioxidant capacity, total oxidant status, and paraoxonase-1 level

et al. 2019

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Breast milk is a well-balanced ideal nutritional source with high bioavailability for infants. As being a fresh, biological and dynamic product, changes in the breast milk during these storage periods have been the subject of ongoing research. This study aims to evaluate total antioxidant capacity (TAC), total oxidant status (TOS), and paraoxonase-1 (PON-1) levels of fresh and freezestored breast milk. Ten cc of breast milk was obtained from the mothers as the days between 10 and 15 in the morning within a 1-hour period. TAC, TOS, and PON-1 levels were evaluated in the fresh breast milk. Collected breast milk samples were divided into two groups for storage at-20°C or-80°C. Stored samples were tested for TAC, TOS, and PON-1 levels after 72 hours. The highest TAC level was detected in fresh breast milk (p <0.05). The TOS levels of fresh breast milk showed a statistically significant reduction in rate after storage. The TOS levels at-20°C and-80°C were significantly lower at-80°C (p <0.05). Our study results show that oxidant and antioxidant activities are at the maximum level in the fresh breast milk. In terms of antioxidant status the effect of freezing temperatures hasn't been determined. We conclude that it is more convenient to store the breast milk at-80°C than to store at-20°C in terms of preserving the storage TOS level.

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“…Within the last years, several studies assessed the TAC of breast milk samples [13,35,36,37,38,39,40,41] collected under various physiological conditions (e.g., different stages of lactation, from mothers delivered term or pre-term). Since the analytical methods to analyze TAC slightly differed in the studies performed, a reliable comparison of the data is difficult.…”

Section: Discussionmentioning

confidence: 99%

Mothers' Consumption of Soy Drink But Not Black Tea Increases the Flavonoid Content of Term Breast Milk: A Pilot Randomized, Controlled Intervention Study

Jochum

Alteheld²,

Meinardus³

et al. 2017

Ann Nutr Metab

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Objective: We performed a pilot RCT to prove the hypothesis that a controlled ingestion of polyphenol-rich beverages (soy drink, decaffeinated black tea) in nutritive dosages by nursing women has an effect on the composition (flavonoid concentration, total antioxidant capacity) of breast milk. Methods: Healthy nursing women were supplemented with either 250 mL of a soy drink (12 mg isoflavones; n = 18), 300 mL decaffeinated black tea (67 mg catechins; n = 18), or 300 mL water (n = 8, control) for 6 days. Milk samples were collected before, during, and after intervention. Flavonoid content (isoflavones/catechins, HPLC) and total antioxidant capacity of milk and test drinks in milk specimens were assessed. Results: Isoflavone content (genistein and daidzein) in breast milk increased up to 12 nmol/L after soy drink consumption; the major flavonoids constituents of black tea (catechin, epicatechin, and respective conjugates) could not be detected in milk samples. With both interventions, the total antioxidant capacity of breast milk was not affected. Conclusions: Mothers' daily consumption of a soy drink considerably increases isoflavone content of breast milk resulting in an estimated daily exposure of 9.6 nmol isoflavones in a 4-month-old suckling infant. Luminal flavanol uptake from black tea consumed by the nursing mother may be too low to affect flavanol concentrations in breast milk.

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The effects of breast milk storage and freezing procedure on interleukine-10 levels and total antioxidant activity

Abstract: The milk stored for 72 h at +4 °C and for 14 d at -20 °C did not maintain the same TAC levels as the fresh samples. This should be considered especially for sick infants who need more antioxidant capability in neonatal units.

Cited by 15 publications

References 21 publications

Review concludes that specific recommendations are needed to harmonise the provision of fresh mother's milk to their preterm infants

Review concludes that specific recommendations are needed to harmonise the provision of fresh mother's milk to their preterm infants

Effects of the storage of breast milk at different temperatures on total antioxidant capacity, total oxidant status, and paraoxonase-1 level

Mothers' Consumption of Soy Drink But Not Black Tea Increases the Flavonoid Content of Term Breast Milk: A Pilot Randomized, Controlled Intervention Study

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