The effects of aromatherapy massage with lavender essential oil on neuropathic pain and quality of life in diabetic patients: A randomized clinical trial

Rivaz, Mozhgan; Rahpeima, Monireh; Khademian, Zahra; Dabbaghmanesh, Mohammad Hossein

doi:10.1016/j.ctcp.2021.101430

Cited by 20 publications

(15 citation statements)

References 36 publications

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Section: Discussionmentioning

confidence: 99%

“…[21] Moreover, massage is a physical therapy method, which can effectively reduce the adverse reactions caused by the long-term use of drugs, and gradually get social recognition in the adjuvant treatment of DPN. [22] However, massage therapy for DPN lacks evidence-based support, so we will conduct a systematic evaluation and metaanalysis on the efficacy and safety of massage adjuvant therapy for DPN, aiming to provide a more powerful clinical basis for massage therapy for DPN.…”

Section: Discussionmentioning

confidence: 99%

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The efficacy and safety of massage adjuvant therapy in the treatment of diabetic peripheral neuropathy

Ren

Guo

et al. 2022

Medicine

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BackgroundThe incidence of diabetic peripheral neuropathy (DPN) is increasing year by year. If patients cannot receive timely and effective treatment, DPN may lead to diabetic foot ulcers or even amputation. This risk factor has been widely concerned around the world. Massage, as a non-invasive physical therapy method, is gradually being applied in the adjuvant treatment of DPN. However, there is no systematic review of the adjuvant treatment of DPN by massage. Our study will explore the effectiveness and safety of massage applied in DPN.MethodsEight electronic databases (PubMed, Cochrane, Web of Science, Sinomed, Embase, China National Knowledge Infrastructure, WanFang Data, Chongqing VIP Information) will be searched by our computer on February 9, 2022. A randomized controlled trial (RCT) of adjuvant massage therapy for DPN was screened. Primary outcome measures: efficiency, nerve conduction velocity. Secondary outcome measures: pain, blood glucose, and incidence of adverse reactions. The quality of the study was evaluated by two researchers using the RCT bias risk assessment tool in the Cochrane review manual Handbook5.4, and meta-analysis was performed by RevMan5.4 software.ResultsRCTs will be used to evaluate the clinical efficacy of massage adjuvant therapy in DPN.ConclusionThis study will provide evidence-based evidence for the safety and effectiveness of massage adjuvant therapy in DPN.Protocol registration number:INPLASY202220025.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The efficacy and safety of massage adjuvant therapy in the treatment of diabetic peripheral neuropathy

Ren

Guo

et al. 2022

Medicine

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“…Nutmeg extracts did not show a significant difference between the treatment group and the control group (p=0.63). Rivaz et al, also showed that herbal medicine therapy could lead to several side effects, such as dizziness, drowsiness, mood disorder, and constipation (24). The use of herbal medicine to overcome the problem of diabetic neuropathy still needs to be continued.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of herbal medicine for patients with diabetic neuropathies: An updated literature review

Hutapea¹,

Simbolon²

2022

Biomedicine

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Traditional medicine is efficacious to protect complications of diabetes mellitus, such as diabetic neuropathy. Therapy with herbal medicine has been developed for people with diabetes empirically over the years. This literature review aims to assess effect of herbal medicine for patients with diabetic neuropathies. We conducted a literature analysis using articles that were randomized controlled clinical trials (RCTs). Three databases were searched from PubMed, EMBASE, CENTRAL that have been published from January 2000 until October 2021until October 2021 and obtained four articles that met the study criteria. The review analysis results showed a significant effect between Gua Sha therapy, green tea extract, and topical Citrullus colocynthis on reducing diabetic neuropathy pain (p < 0.05). Nutmeg Extracts did not show significant results on diabetes mellitus pain after being treated for four weeks (p = 0.063). The review results in the physical and neural function also showed the significant increase in mean scores. Despite the positive findings, it is too early to conclude on the efficacy of herbal medicine to treat diabetic neuropathy due to the high clinical heterogeneity and the number of sample size of the study was too small. However, it may be indicative of the effect of herbal medicine in reducing pain in diabetic neuropathy.

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“…They looked at both pain scores and QoL metrics for diabetic neuropathy patients randomized to receive 10 min of foot massage with 10% lavender oil in sunflower oil for one month at outpatient clinics in Iran. They found a significant increase in QoL metrics and a decrease in neuropathic pain at the four-week mark [ 25 ].…”

Section: Lavender (Lavendula) For Neuropathic Painmentioning

confidence: 99%

Essential Oils and Neuropathic Pain

Ridouh¹,

Hackshaw

2022

Plants

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Neuropathic pain is one of the most prominent chronic pain syndromes, affecting almost 10% of the United States population. While there are a variety of established pharmacologic and non-pharmacologic treatment options, including tricyclic antidepressants (TCAs), serotonin-noradrenaline reuptake inhibitors, anticonvulsants, trigger point injections, and spinal cord stimulators, many patients continue to have chronic pain or suboptimal symptom control. This has led to an increased interest in alternative solutions for neuropathic pain such as nutritional supplements and essential oils. In this review, we explore the literature on the most commonly cited essential oils, including lavender, bergamot, rosemary, nutmeg, Billy goat weed, and eucalyptus. However, the literature is limited and largely comprised of preclinical animal models and a few experimental studies, some of which were poorly designed and did not clearly isolate the effects of the essential oil treatment. Additionally, no standardized method of dosing or route of administration has been established. Further randomized control studies isolating the active components of various essential oils are needed to provide conclusive evidence on the use of essential oils for neuropathic pain. In this review, we explore the basis behind some of the essential oils of interest to patients with neuropathic pain seen in rheumatology clinics.

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The effects of aromatherapy massage with lavender essential oil on neuropathic pain and quality of life in diabetic patients: A randomized clinical trial

Cited by 20 publications

References 36 publications

The efficacy and safety of massage adjuvant therapy in the treatment of diabetic peripheral neuropathy

The efficacy and safety of massage adjuvant therapy in the treatment of diabetic peripheral neuropathy

Efficacy of herbal medicine for patients with diabetic neuropathies: An updated literature review

Essential Oils and Neuropathic Pain

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