Ageing is associated with a decrease in physical performance implying that aged manual workers may be unable to match the physical requirements of their jobs. In this cross-sectional study, 96 male manual workers aged 51-72 years were recruited. Outcomes included handgrip strength (HGS), fat-free mass (FFM), fat percentage, cardiorespiratory fitness (Vo 2 max), forced vital capacity (FVC), forced expiratory volume after 1 s (FEV 1 ), spinal flexibility, sit-to-stand test performance and static balance. Covariates included height, smoking habits, leisure-time physical activity and systemic inflammation from blood samples. Outcomes were also compared with general populations. Age was negatively related to FFM and FEV 1 , whereas static balance (velocity of displacement) was positively associated with age. Greater HGS, but poorer Vo 2 max and FEV 1 /FEV ratio were found compared with general populations. Age was negatively related with physical performances although a large part of the variance in performance could be explained by factors other than age such as smoking and systemic inflammation. The manual workers had greater muscle strength but had poorer cardiorespiratory fitness and lung function when compared with general populations. Specific health interventions targeting specifically cardiorespiratory fitness, lung function, and balance may be needed to maintain physical performances among manual workers.Noticeable age-related reductions in physical performance typically start beyond the third 1 and accelerate after the fifth decade of life 2-5 . These changes include reduced muscle strength 3 and cardiorespiratory fitness 4 , altered body composition 2 and impaired lung function 4 . Together, these adverse effects of ageing eventually culminate in diminished physical performances and mobility impairments 6,7 . An inactive life style has been ascribed as an important factor contributing to such changes and increasing physical activity-through either aerobic or resistance-based exercise-may mitigate some of the negative effects of age on physical performances 6,8 .Adults who have physically demanding jobs are inherently physically active in their working life. Intuitively, this should retain their physical performance to a greater extent than that of people doing sedentary work 8-10 . However, the physical activities performed by manual workers may help in maintaining muscle strength 11 , but do not seem to improve cardiorespiratory fitness [11][12][13][14][15] . Moreover, a recent systematic review has shown that high occupational physical activity increases the risk of all-cause mortality by 18% 16 . Average life expectancy has steadily increased over the last century, which has led policymakers to pass laws that increase retirement age in an attempt to accommodate the growing population of senior workers. The effect of increasing retirement age may therefore be to shorten the years lived in good health for manual workers 17 . Although muscle strength is reportedly higher in manual workers when compared with...