The Effects of Aerobic Exercise on N-terminal Pro-B-type Natriuretic Peptide and Cardiopulmonary Function in Patients With Heart Failure: A Meta-Analysis of Randomised Clinical Trials

The role of exercise training on cardiovascular peptides in patients with heart failure: A systematic review and meta-analysis

“…It is possible that an optimal increase in BNP and NT-proBNP following exercise training intervention resulted in the regulation of cardiac function, increased physiological adaptations in left ventricular function, vasodilation and natriuresis in healthy humans ( Maeder et al, 2008 ). However, a decrease in BNP and NT-proBNP values following exercise training has a positive adaptation on CVS in HF patients ( McDonagh et al, 2021 ; Santoso et al, 2020 ; Pearson et al, 2018 ), which was observed after aerobic exercise training for NT-proBNP marker, irrespective of overweight/obese status, in our systematic review and meta-analysis. The findings of our systematic review and meta-analysis were consistent with the results of previous systematic review and meta-analysis studies ( Santoso et al, 2020 ; Pearson et al, 2018 ; Cipriano et al, 2014 ; Smart et al, 2012 ; Smart and Steele, 2010 ) and were inconsistent with others ( Pearson et al, 2018 ; Smart et al, 2012 ; Smart and Steele, 2010 ).…”

Effects of Aerobic Training on Cardiopulmonary Function Based on Multiple Linear Regression Analysis

“…The specific reports about heart and lung are as follows: the common clinical manifestations are fatigue and weakness, sleep disorder, loss of appetite, low mood, upset, memory loss, etc., which affect social interaction and all aspects of life. More severe patients need treatment to improve symptoms and quality of life [ 2 ]. Studies have found that aerobic exercise can improve the hemodynamic state, improve the activity of myocardial cell oxidase and promote neuroendocrine effects, then improve heart rate, maximum cardiac output, stroke volume, and other cardiac functions, improve symptoms such as shortness of breath, and enhance self-care ability in daily life [ 3 ].…”

Effect of different intensity exercises intervention on cardiovascular functions and quality of life on patients with chronic heart failure

“…Indeed, Santoso et al have demonstrated that aerobic exercise improves the N-terminal pro-B-type natriuretic peptide, ventilatory efficiency, aerobic capacity, maximal workload, and left ventricular function in patients with CHF. [ 6 ] In addition, a meta-analysis showed that CHF patients could benefit more from resistance training programs. [ 7 ] To date, several systematic reviews have examined the effects of different forms of exercise on patients with CHF.…”