The Effects of a Single Electronic Music Improvisation Session on the Pain of Adults with Sickle Cell Disease: A Mixed Methods Pilot Study

Rodgers-Melnick, Samuel N; Matthie, Nadine; Jenerette, Coretta; Pell, Tara J Griest; Lane, Deforia; Fu, Pingfu; Margevicius, Seunghee; Little, Jane A.

doi:10.1093/jmt/thy004

Cited by 17 publications

(29 citation statements)

References 37 publications

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“…In our prior three-arm randomized controlled trial comparing 1) music therapy, 2) music listening, and 3) no music (control), 20 we found that participants with SCD who received a single 20-minute electronic music improvisation session with a music therapist reported significant improvements in pain intensity and mood compared to a control group, whereas participants who received music listening only reported improvements in mood. Qualitative data from this study supported the acceptability and feasibility of a single music therapy intervention for addressing acute pain during an acute care clinic visit.…”

Section: Introductionmentioning

confidence: 91%

Effects of Music Therapy on Quality of Life in Adults with Sickle Cell Disease (MUSIQOLS): A Mixed Methods Feasibility Study

Rodgers-Melnick

Lin

Gam

et al. 2022

JPR

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Purpose: To investigate the feasibility, acceptability, and preliminary efficacy of a 6-session music therapy protocol on self-efficacy, quality of life, and coping skills in adults with sickle cell disease (SCD). Patients and Methods: Using a mixed-methods intervention design, adults with SCD (ages 21-57; mean age 32.33) were randomized (1:1) to either 1) a 6-session music therapy (MT) intervention (n = 12) or 2) waitlist control (WLC) (n = 12) using stratified randomization where factors were age in years (≤30 vs >30), and sex (male, female). All participants completed two weeks of daily electronic pain diary entries and self-efficacy, quality of life, and coping skills measures before and after their assigned study condition to explore preliminary efficacy. MT participants were taught music exercises accessed via smartphone and subsequently interviewed to determine feasibility and acceptability. Results: The enrollment rate was 89%. All study measures were completed, with high rates of electronic pain diary completion at baseline (70%) and 2-week follow-up (66%). Interviews revealed two overall themes related to MT participants' experience: 1) participants learned new self-management skills and 2) MT improved participants' ability to cope with pain. MT participants demonstrated 100% attendance. In preliminary analyses, MT participants demonstrated significant improvements (means ± SD) in self-efficacy (5.42 ± 5.43, p = 0.008, d = 1.20), PROMIS sleep disturbance (−1.49 ± 6.68, p = 0.023, d = −0.99), PROMIS pain interference (−2.10 ± 4.68, p = 0.016, d = −1.06), and ASCQ-Me social functioning impact scores (2.97 ± 6.91, p = 0.018, d = 1.05) compared to WLC participants. Conclusion: Preliminary findings support the feasibility and acceptability of music therapy for home use in adults with SCD. While music therapy may assist adults with SCD in improving self-efficacy and quality of life, subsequent, fully-powered clinical research is needed to determine its efficacy.

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Section: Introductionmentioning

confidence: 91%

Effects of Music Therapy on Quality of Life in Adults with Sickle Cell Disease (MUSIQOLS): A Mixed Methods Feasibility Study

Rodgers-Melnick

Lin

Gam

et al. 2022

JPR

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“…Beyond pharmacologic measures, interventions such as cognitive behavioral therapy, acupuncture, mindfulness, and yoga have demonstrated effectiveness in pain management for individuals with SCD (Mahmood et al, 2020;Moody et al, 2017;Simmons et al, 2019). Distraction from pain through participation in music and virtual reality are also helpful to decreasing pain (Diaz-Hennessy & O'Shea, 2019;Rodgers-Melnick et al, 2018). In fact, researchers have determined that listening to music carries benefits beyond distraction from pain such as regulating mood, focusing attention on studies, relaxing, and connecting with others (Solodiuk et al, 2020).…”

Section: Pain Managementmentioning

confidence: 99%

Sickle Cell Disease Care Planning for School Nurses

et al. 2021

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Schoolchildren with sickle cell disease (SCD) experience physiologic and psychologic stress that can affect school functioning, mental well-being, and physical health. Student needs are unique and individualized; however, school nurses can support students and families with SCD through comprehensive and thorough care planning efforts. In addition to components specific to individual prescriptions and other nonpharmacological therapies, school nurses should consider school access and inclusion, pain management, racism, and disease self-management when care planning. As a healthcare provider who may have several continuous years of near-daily contact with students, the school nurse is an imperative provider, educator, and advocate for students learning to manage their SCD and avoid the related complications and challenges.

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“…Transfusion is carried out using simple transfusion or exchange transfusion. 82 Rodgers-Melnick et al 105 revealed that standard care and 20 minutes of electronic music improvisation with a board-certified music therapist improved visual analogue scale of pain intensity of SCD patients compared to control using a three-group mixed methods intervention designed study. A retrospective review showed 13 SCD patients who received inpatient acupuncture treatment for acute VOC revealed a reduction in reported pain score immediately after the acupuncture treatment.…”

Section: Current Treatment Of Pain In Scdmentioning

confidence: 99%

“…106 These and other modalities, such as transcutaneous electrical nerve stimulation (TENS), heat, cold and vibration, relaxation, distraction, massage, music, guided imagery, self-hypnosis, self-motivation, acupuncture and biofeedback have been used in controlling pain in SCD; however, there are no controlled clinical studies to support their use. 10,105,[107][108][109][110] Possible targets of pain treatment of SCD and future possibility. Many pharmacological treatments targeting one or more of the mechanisms that contribute to the pain relief or the disease process of SCD are being explored in clinical trials.…”

Section: Current Treatment Of Pain In Scdmentioning

confidence: 99%

Mechanisms of pain in sickle cell disease

Takaoka

Cyril

Jinesh

et al. 2020

British Journal of Pain

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Objectives: The hallmark of sickle cell disease (SCD) is acute and chronic pain, and the pain dominates the clinical characteristics of SCD patients. Although pharmacological treatments of SCD targeting the disease mechanisms have been improved, many SCD patients suffer from pain. To overcome the pain of the disease, there have been renewed requirements to understand the novel molecular mechanisms of the pain in SCD. Methods: We concisely summarized the molecular mechanisms of SCD-related acute and chronic pain, focusing on potential drug targets to treat pain. Results: Acute pain of SCD is caused by vaso-occulusive crisis (VOC), impaired oxygen supply or infarction-reperfusion tissue injuries. In VOC, inflammatory cytokines include tryptase activate nociceptors and transient receptor potential vanilloid type 1. In tissue injury, the secondary inflammatory response is triggered and causes further tissue injuries. Tissue injury generates cytokines and pain mediators including bradykinin, and they activate nociceptive afferent nerves and trigger pain. The main causes of chronic pain are from extended hyperalgesia after a VOC and central sensitization. Neuropathic pain could be due to central or peripheral nerve injury, and protein kinase C might be associated with the pain. In central sensitization, neuroplasticity in the brain and the activation of glial cells may be related with the pain. Discussion: In this review, we summarized the molecular mechanisms of SCD-related acute and chronic pain. The novel treatments targeting the disease mechanisms would interrupt complications of SCD and reduce the pain of the SCD patients.

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The Effects of a Single Electronic Music Improvisation Session on the Pain of Adults with Sickle Cell Disease: A Mixed Methods Pilot Study

Abstract: Preliminary findings were promising and support the need for additional studies evaluating improvisational music therapy interventions for acute pain management in adults with SCD.

Cited by 17 publications

References 37 publications

Effects of Music Therapy on Quality of Life in Adults with Sickle Cell Disease (MUSIQOLS): A Mixed Methods Feasibility Study

Effects of Music Therapy on Quality of Life in Adults with Sickle Cell Disease (MUSIQOLS): A Mixed Methods Feasibility Study

Sickle Cell Disease Care Planning for School Nurses

Mechanisms of pain in sickle cell disease

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