The effectiveness of Аlflutop in vertebral neurology

Oros, M.M.; Salamova, Н.М.; Kampov, N.M.; Pavlyk, А.О.; Semerenko, O.O.; Sychevska, L.L.; Yusypovych, T.D.

doi:10.22141/2224-0713.17.4.2021.237600

INJ

2021

DOI: 10.22141/2224-0713.17.4.2021.237600

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The effectiveness of Аlflutop in vertebral neurology

M.M. Oros

Н.М. Salamova

N.M. Kampov

et al.

Abstract: Alflutop is the standardized sterile extract of marine fish, similar in composition to the matrix of hyaline cartilage, manufactured by Biotehnos S.A. (Romania). The question of the effectiveness of aflutop remains relevant.

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Effectiveness of the use of bioactive concentrate of marine fish in patients with back pain

Oros,

Fister,

Akimov

et al. 2024

PJS

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Background. The urgency of pain relief and patient improvement necessitates evaluating the most effective treatment approaches. This includes a comparative analysis of medications with different mechanisms of action, both taken individually and in combination while considering potential drug toxicity and individual patient intolerances. The study purposed to assess the efficacy of a bioactive concentrate derived from marine fish (BCMF), both alone and in combination with a non-steroidal anti-inflammatory drug (NSAID), for the treatment of back pain, in comparison to therapy involving solely oral sodium chondroitin sulfate (CS). Materials and methods. We examined four groups of patients, each comprising 30 male or female subjects with complaints of back pain. Each group was administered one of three medications: NSAIDs in a standard dosage, CS in a daily dose of 1 g (two capsules of 500 mg each), and BCMF in the form of intramuscular injections in a daily dose of 1 ml (0.2 ml per injection). The fourth group of patients received combined treatment, namely, 1 ml of BCMF and NSAIDs in a standard dosage daily. All participants underwent laboratory tests and instrumental examinations. Results. The administration of BCMF, both alone and in combination with NSAIDs resulted in an improved subjective assessment of patients’ psychoemotional well-being, marked by reduced back pain intensity, enhanced quality of life indices, and diminished levels of anxiety and depression. The combination of BCMF with NSAIDs demonstrated a more pronounced effect on reducing tumor necrosis factor α serum concentration than monotherapy with BCMF. The combination therapy positively impacted the condition of lower extremity vessels as indicated by Doppler ultrasonography. Conclusions. BCMF can be an effective addition to the standard therapy of back pain.

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Effectiveness of the use of bioactive concentrate of marine fish in patients with back pain

Oros,

Fister,

Akimov

et al. 2024

PJS

View full text Add to dashboard Cite

show abstract

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The effectiveness of Аlflutop in vertebral neurology

Abstract: Alflutop is the standardized sterile extract of marine fish, similar in composition to the matrix of hyaline cartilage, manufactured by Biotehnos S.A. (Romania). The question of the effectiveness of aflutop remains relevant.

Cited by 1 publication

References 1 publication

Effectiveness of the use of bioactive concentrate of marine fish in patients with back pain

Effectiveness of the use of bioactive concentrate of marine fish in patients with back pain

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