The effectiveness of ultrasonography and ultrasonographic elastography in the diagnosis of carpal tunnel syndrome and evaluation of treatment response after steroid injection

Asadov, Ruslan; Erdal, Ayşe; Bugdayci, Onur; Gündüz, Osman Hakan; Ekinci, Gazanfer

doi:10.1016/j.ejrad.2018.09.027

Cited by 24 publications

(27 citation statements)

References 25 publications

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“…5 ). This confirmed that the therapeutic outcome of CTS could be evaluated independently with SE, as validated earlier under other conditions by other researchers ( 3 , 15 , 16 ) . Tissue softening may have clinical implications, as it may be indicative of the beneficial consequences of the rehabilitation process.…”

Section: Discussionsupporting

confidence: 88%

“…4 ). Although the treatment strategy is different in principle when corticosteroid is locally injected to the carpal tunnel, the nerve area exhibited a slight increase in mild cases, but a significant decrement in moderate cases ( 3 ) .…”

Section: Discussionmentioning

confidence: 99%

“…Ultrasonography (US) has been suggested as a non-invasive and inexpensive tool for the visualization of the entire median nerve and its surroundings ( 3 ) . Past data supports the utilization of US not only in the initial diagnosis of CTS, but also in determining the efficacy of applied therapy ( 4 – 6 ) .…”

Section: Introductionmentioning

confidence: 99%

“…In a limited number of papers, SE has been successfully utilized for the diagnosis of CTS, and the median nerve in patients with CTS has been reported to be stiffer than in healthy individuals ( 10 , 13 – 15 ) . The beneficial utility of SE as a new way of assessing the therapeutic outcome has also been demonstrated after steroid injection into the carpal tunnel ( 3 , 15 ) or following the release of the flexor retinaculum ( 16 ) .…”

Section: Introductionmentioning

confidence: 99%

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Sonoelastic response of median nerve to rehabilitation in carpal tunnel syndrome

et al. 2020

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Aim of the study To evaluate the sonoelastic response of the median nerve in patients with carpal tunnel syndrome following conservative rehabilitation with splint plus exercise regimens. Materials and methods A total of thirty-five patients diagnosed with mild carpal tunnel syndrome and treated with splint plus exercise therapy; hand resting splint all day for 3 weeks and then only at nights along with nerve gliding exercises in 10 repetitions 3 times a day. The median nerve was evaluated clinically prior to the treatment and at week 6 of therapy using physical examination, electrodiagnostic neurophysiology tests and radiological imaging; Boston Scores, electromyogram, ultrasonography and sonoelastography. Results Following the 6-week treatment protocol on 35 subjects with mild carpal tunnel syndrome, sonoelastography showed significantly softer median nerve, while the traditional parameters based on Boston Scores and cross-sectional area based on ultrasonography remained nearly unresponsive. Such early indication of biomechanical changes in the nerve may be of clinical importance if it can offer a prognostic value of the applied treatment, while tissue softening suggests the alleviation of nerve compression. Conclusions Sonoelasticity of the median nerve can serve as a reliable marker for assessing therapeutic changes in median nerve stiffness and potentially the outcome early on in mild carpal tunnel syndrome.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Sonoelastic response of median nerve to rehabilitation in carpal tunnel syndrome

et al. 2020

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“…Median nerve stiffness decreases significantly after carpal tunnel release, associated with reduction in symptoms. 20,44 It was also shown that the elastographic parameters improved more consistently before changes in nerve morphology, indicating that nerve ultrasound (Continues) elastography may be a more sensitive measure of nerve recovery than CSA. 20 Similar changes were identified after treatment with low level laser energy and splinting.…”

Section: Cts and The Median Nervementioning

confidence: 98%

Ultrasound elastography for the evaluation of peripheral nerves: A systematic review

Wee

Simon

2019

Muscle and Nerve

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Peripheral nerve disorders are commonly encountered in clinical practice. Electrodiagnostic studies remain the cornerstone of the evaluation of nerve disorders. More recently, ultrasound has played an increasing complementary role in the neuromuscular clinic. Ultrasound elastography is a technique that measures the elastic properties of tissues. Given the histological changes that occur in diseased peripheral nerves, nerve ultrasound elastography has been explored as a noninvasive way to evaluate changes in nerve tissue composition. Studies to date suggest that nerve stiffness tends to increase in the setting of peripheral neuropathy, regardless of etiology, consistent with loss of more compliant myelin, and replacement with connective tissue. The aim of this systematic review is to summarize the current literature on the use of ultrasound elastography in the evaluation of peripheral neuropathy. Limitations of ultrasound elastography and gaps in current literature are discussed, and prospects for future clinical and research applications are raised.

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Peripheral Nerves

Bedewi

2023

Elastography of the Musculoskeletal System

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The effectiveness of ultrasonography and ultrasonographic elastography in the diagnosis of carpal tunnel syndrome and evaluation of treatment response after steroid injection

Cited by 24 publications

References 25 publications

Sonoelastic response of median nerve to rehabilitation in carpal tunnel syndrome

Sonoelastic response of median nerve to rehabilitation in carpal tunnel syndrome

Ultrasound elastography for the evaluation of peripheral nerves: A systematic review

Peripheral Nerves

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