Background
Children with craniofacial disorders are at increased risk for obstructive sleep apnea syndrome (OSAS). Methods for diagnosing OSAS in this population remain controversial. Sleep studies are the gold standard but are impractical for all patients. The utility of OSAS questionnaires like the Pediatric Sleep Questionnaire (PSQ) is unknown in children with craniofacial disorders. We hypothesized that the PSQ would be a sensitive tool for detecting OSAS in children with craniofacial abnormalities.
Methods
A retrospective review of consecutive children with diagnosed craniofacial disorders who both completed the PSQ and had a polysomnogram (PSG) was performed. Demographics, PSQ score, and PSG data were recorded. Statistical analysis included calculation of sensitivity, specificity, positive predictive value (PPV), and negative predictive values (NPV) for the PSQ.
Results
83 children 2–18 years old were included in the study. Of these, 44 (53.0%) screened positive on the PSQ and 23 (27.7%) had PSG evidence of OSAS, but the sensitivity of the PSQ for detecting OSAS in this sample was only 0.57 and the specificity was 0.48. PPV and NPV were 0.30 and 0.74, respectively. The correlation between the apnea hypopnea index and PSQ score was 0.152 (p=0.17).
Conclusions
A substantial portion of craniofacial patients referred for PSG was found to have OSAS. However, the PSQ is not a good screening tool for OSAS in children with craniofacial conditions. More research is needed to determine which patients with craniofacial disorders should be evaluated for OSAS by PSG or other means.
LEVEL OF EVIDENCE
Diagnostic, III