“…Recently, photon‐initiated photoacoustic streaming (PIPS) with Er:YAG laser at low pulse energy (20 mJ) and short pulse duration (50 μs) was introduced in root canal irrigation (Balic et al, ; DiVito, Peters, & Olivi, ). The technology is based on the mechanism of bubble cavitation involving strong shockwaves due to collapse of bubbles in a fluid and is effective in removing the smear layer from the surrounding walls (Nasher, Franzen, & Gutknecht, ). Studies evaluating the efficacy of PIPS in endodontic treatment revealed that it is a potential technique for elimination of the smear layer and dentinal debris (Passalidou, Calberson, De Bruyne, De Moor, & Meire, ; Verstraeten, Jacquet, De Moor, & Meire, ); however, those authors did not perform systematic comparison of antimicrobial efficacy among irrigation solutions in routine use combined with PIPS.…”