IntroductionProblem-oriented learning (POL) in medical education is a student-centric mode of teaching-learning in which students learn about a topic by solving a problem presented in the shared resource material. 1,2 The overall process of problem solving does not emphasize a specific solution, but rather enables the learner to devise their own unique solutions, and, in the process, acquire other desirable skills. 1,2 These include the acquisition of knowledge, critical thinking, critical appraisal, clinical reasoning, learning literature review, team work and improved communication skills. 2 Broadly, the entire process is comprised of three steps: problem analysis, self-directed learning, and reporting, all of which are interdependent and prepare the students for better learning. 3 In order to develop competent health care professionals and to help medical students to acquire clinical reasoning, critical thinking and problem-solving skills, integrated teaching has been initiated at a medical college for the first and second years of undergraduation. As a part of the implementation of integrated learning, POL sessions were established in the second year of undergraduate education of medical students in a medical college. One hundred and fifty students were divided into 10 sets of 15 members each. The objective of the study was to measure the effectiveness of POL sessions in increasing medical Abstract Background: In order to develop competent health care professionals and to help medical students to acquire clinical reasoning, critical thinking and problem-solving skills, it was decided to initiate problem-oriented learning (POL) sessions as a part of implementation of integrated learning in the second year of undergraduate education of medical students in a medical college.