The Effectiveness of Nursing Intervention Program on Emotional Distress, Self-Efficacy, and Liver Enzymes Among Hepatitis C Virus Patients Undergoing Antiviral Treatment Therapy (Sovaldi Medication)

Abstract

Almost all patients receiving hepatitis C antiviral therapy will experience some treatment-related adverse effects.Emotional distress and fatigue can lead to early treatment discontinuation. Close monitoring is crucial throughout treatment. The nurses can promote adherence by counseling patients on the recognition and management of treatment-related adverse effects. The purpose of the study was to evaluate the effectiveness of nursing intervention program on emotional distress, selfefficacy and liver enzymes among hepatitis C Virus patients undergoing antiviral treatment therapy (Sovaldi medication). Quasi experimental design (one group pre/posttest) was used to achieve the aim of the study. The study was conducted in the Liver Institute at Shebin El kom District, Menoufia Governorate. A purposeful sample of 50 patients with hepatitis C virus patients undergoing antiviral treatment therapy (Sovaldi medication) from the above setting were recruited. Three instrument were used for data collection (1): Structured interview questionnaire to assess demographic and clinical data (2): Hospital anxiety and depression scale to measure emotional distress. (3): Self-efficacy scale to measure patients' self-efficacy. The result revealed that there were statistical significant improvements of patient's knowledge, patients' emotional distress, liver enzymes and self-efficacy post program than preprogram. Conclusion: Nursing intervention program is the key element for management of patients' emotional distress, self-efficacy and reduction of liver enzymes. Recommendation: psych educational program should be given for all patients with hepatitis C virus undergoing antiviral treatment therapy to improve their knowledge about the drug and promote adherence by counseling patients on the recognition and management of treatment related adverse effect. Encourage them to discuss their problem with health care team and participate in self-help program to decrease emotional distress and increase self-efficacy.

Development and Evaluation of an Antiviral Agent Medication Adherence Education Program for Patients with Chronic Hepatitis C

“…The AMAEP for patients with CHC also improved patients’ self-efficacy in taking antiviral drugs compared with the control group, which is similar to the results of previous studies [ 9 , 35 , 36 ]. This may be because this program recognized the need for antiviral drugs and confirmed the treatment goals through education, which improved patients’ understanding of the disease.…”

“…Self-efficacy is the main variable in medicine administration and patients with higher self-efficacy tend to be more efficient in adhering to their treatment, which affects the treatment results [ 7 ]. Since not taking medication leads to discontinuation of the treatment, it is important to actively monitor the treatment process, particularly medication use among patients [ 8 , 9 ]. Misuse has been defined as the incorrect use of an over-the-counter (OTC) product for a medical purpose, usually in regard to dosage or duration of use [ 10 ].…”

Educational Nursing Program Implementation: It’s Effect on Hepatic Encephalopathy Severity among Patients with Liver Cirrhosis

“…These findings are supported by Sabola et al, (2022) who found that there was an improvement in all mean score of patients' laboratory data. Also, these results are consistent with Malky et al, (2016) who indicated highly significant reduction of liver enzymes post intervention than pre-intervention.…”

Categorization and Characterization of Activities Designed to Help Health-care Professionals Involved in Hepatitis Care Increase Their Awareness of the Disease: The Classification of Hepatitis Medical Care Coordinators

“…Clinical nurses have regular contact with patients in outpatient clinics and hospital wards. The physical and psychological support clinical nurses provide to hepatitis C patients receiving antiviral treatment has been found to have a positive effect, as it increases adherence to medication (23,24). Previous studies have shown that educational interventions by clinical nurses have helped patients increase their understanding of hepatitis C and improve their QOL (25)(26)(27)(28).…”