The effectiveness of mapping-targeted biopsies on the index lesion in transperineal prostate biopsies
Nahuel Paesano,
Violeta Catalá,
Larisa Tcholakian
et al.
Abstract:Purpose: To evaluate the eff ectiveness of mapping-targeted biopsies (MTB) on the index lesion for the detection of clinically significant prostate cancer (csPCa) in transperineal fusion-image prostate biopsies.
Materials and Methods:A retrospective analysis was conducted on 309 men with suspected PCa who underwent prostate biopsies at the Creu Blanca reference center in Barcelona, Spain. The Prostate Imaging-Reporting and Data System (PI-RADS v.2.1) of the magnetic resonance images (MRI) were reclassified by … Show more
“…Dr. Paesano and collegues from Spain, performed in page 296 ( 4 ) a nice study about the effectiveness of mapping-targeted biopsies on the index lesion in transperineal prostate biopsies and concluded that this model had the potential to avoid 23.3% of prostate biopsies without missing additional csPCa cases. Mapping-targeted biopsies of the index lesion was highly effective for identifying clinically significant prostate cancer (csPCa) in fusion transperineal prostate biopsies.…”
and USA, and as usual the editor ś comment highlights some of them. The editor in chief would like to highlight the following works:Dr. Andrade and collegues from Brazil, presented in page 237 (1) a nice systematic review about the outcomes of ablative therapy and radical treatment for prostate cancer and concluded that the biochemical recurrence and urinary continence outcomes of ablative therapy and radical treatment were similar. Ablative therapy appears to have a high rate of sexual potency.Dr. Lepine and collegues from Brazil, presented in page 250 (2) we can obseve an important sytematic review about the intraoperative Computed Tomography (ICT) for detection of residual stones in endourology procedures and concluded that the use of ICT scans during PCNL significantly increases success rates when compared to the standard fluoroscopy-guided detection of residual stones. Our findings also indicate decreased reintervention rates, with no statistically significant differences in complication rates.Dr. Gomes and collegues from Brazil performed in page 287 (3) an interesting study about theurinary tract symptoms in a prospective cohort of COVID-19 survivors and concluded that LUTS are highly prevalent and bothersome six months after hospitalization due to COVID-19. Assessment of LUTS may help ensure appropriate diagnosis and treatment in these patients.Dr. Paesano and collegues from Spain, performed in page 296 (4) a nice study about the effectiveness of mapping-targeted biopsies on the index lesion in transperineal prostate biopsies and concluded that this model had the potential to avoid 23.3% of prostate biopsies without missing additional csPCa cases. Mapping-targeted biopsies of the index lesion was highly effective for identifying clinically significant prostate cancer (csPCa) in fusion transperineal prostate biopsies. A developed predictive model successfully reduced the need for almost one quarter of biopsies without missing csPCa cases.Dr. Manfredi and collegues from Italy performed in page 309 (5) a study about the new technologies in BPH treatment. The authors shows the long term functional outcomes and surgical retreatment after thulium laser enucleation of prostate and concluded that ThuLEP is associated with optimal functional outcomes and a low frequency of
“…Dr. Paesano and collegues from Spain, performed in page 296 ( 4 ) a nice study about the effectiveness of mapping-targeted biopsies on the index lesion in transperineal prostate biopsies and concluded that this model had the potential to avoid 23.3% of prostate biopsies without missing additional csPCa cases. Mapping-targeted biopsies of the index lesion was highly effective for identifying clinically significant prostate cancer (csPCa) in fusion transperineal prostate biopsies.…”
and USA, and as usual the editor ś comment highlights some of them. The editor in chief would like to highlight the following works:Dr. Andrade and collegues from Brazil, presented in page 237 (1) a nice systematic review about the outcomes of ablative therapy and radical treatment for prostate cancer and concluded that the biochemical recurrence and urinary continence outcomes of ablative therapy and radical treatment were similar. Ablative therapy appears to have a high rate of sexual potency.Dr. Lepine and collegues from Brazil, presented in page 250 (2) we can obseve an important sytematic review about the intraoperative Computed Tomography (ICT) for detection of residual stones in endourology procedures and concluded that the use of ICT scans during PCNL significantly increases success rates when compared to the standard fluoroscopy-guided detection of residual stones. Our findings also indicate decreased reintervention rates, with no statistically significant differences in complication rates.Dr. Gomes and collegues from Brazil performed in page 287 (3) an interesting study about theurinary tract symptoms in a prospective cohort of COVID-19 survivors and concluded that LUTS are highly prevalent and bothersome six months after hospitalization due to COVID-19. Assessment of LUTS may help ensure appropriate diagnosis and treatment in these patients.Dr. Paesano and collegues from Spain, performed in page 296 (4) a nice study about the effectiveness of mapping-targeted biopsies on the index lesion in transperineal prostate biopsies and concluded that this model had the potential to avoid 23.3% of prostate biopsies without missing additional csPCa cases. Mapping-targeted biopsies of the index lesion was highly effective for identifying clinically significant prostate cancer (csPCa) in fusion transperineal prostate biopsies. A developed predictive model successfully reduced the need for almost one quarter of biopsies without missing csPCa cases.Dr. Manfredi and collegues from Italy performed in page 309 (5) a study about the new technologies in BPH treatment. The authors shows the long term functional outcomes and surgical retreatment after thulium laser enucleation of prostate and concluded that ThuLEP is associated with optimal functional outcomes and a low frequency of
Since the optimal scheme for targeted biopsies of magnetic resonance imaging (MRI) suspicious lesions remains unclear, we compare the efficacy of two schemes for these index lesions. A prospective trial was conducted in 1161 men with Prostate Imaging Reporting and Data System v 2.1 3–5 undergoing targeted and 12-core systematic biopsy in four centers between 2021 and 2023. Two- to four-core MRI-transrectal ultrasound fusion-targeted biopsies via the transperineal route were conducted in 900 men in three centers, while a mapping per 0.5 mm core method (saturated scheme) was employed in 261 men biopsied in another center. A propensity-matched 261 paired cases were selected for avoiding confounders other than the targeted biopsy scheme. CsPCa (grade group ≥ 2) was identified in 125 index lesions (41.1%) when the two- to four-core scheme was employed, while in 187 (71.9%) when the saturated biopsy (p < 0.001) was used. Insignificant PCa (iPCa) was detected in 18 and 11.1%, respectively (p = 0.019). Rates of csPCa and iPCa remained similar in systematic biopsies. CsPCa detected only in systematic biopsies were 5 and 1.5%, respectively (p = 0.035) in each group. The saturated scheme for targeted biopsies detected more csPCa and less iPCa than did the two- to four-core scheme in the index lesions. The rate of csPCa detected only in the systematic biopsies decreased when the saturated scheme was employed.
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