The effectiveness of manual therapy on pain, physical function, and nerve conduction studies in carpal tunnel syndrome patients: a systematic review and meta-analysis

Jiménez‐del‐Barrio, Sandra; Cadellans-Arróniz, Aïda; Ceballos‐Laita, Luis; Estébanez-de-Miguel, Elena; López-de-Celis, Carlos; Bueno-Gracía, Elena; Pérez‐Bellmunt, Albert

doi:10.1007/s00264-021-05272-2

Cited by 30 publications

(19 citation statements)

References 50 publications

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“…NCS allows an evaluation of the large fibers (myelinated alpha and beta), while with this tool it is not possible to identify the function of the small fibers (small myelinated Aδ-fibers and unmyelinated C-fibers) [ 120 , 121 ]. The application of skin electrodes permits nerve stimulation in μV and the detection of electrical nerve activity through a series of parameters that are useful for diagnosing nerve and muscle fiber pathologies [ 120 , 122 , 123 , 124 , 125 ]. The parameters mainly used are velocity nerve conduction, amplitudes, and latencies.…”

Section: Diagnosismentioning

confidence: 99%

Peripheral Neuropathy in Diabetes Mellitus: Pathogenetic Mechanisms and Diagnostic Options

Galiero

Caturano

Vetrano

et al. 2023

IJMS

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Diabetic neuropathy (DN) is one of the main microvascular complications of both type 1 and type 2 diabetes mellitus. Sometimes, this could already be present at the time of diagnosis for type 2 diabetes mellitus (T2DM), while it appears in subjects with type 1 diabetes mellitus (T1DM) almost 10 years after the onset of the disease. The impairment can involve both somatic fibers of the peripheral nervous system, with sensory-motor manifestations, as well as the autonomic system, with neurovegetative multiorgan manifestations through an impairment of sympathetic/parasympathetic conduction. It seems that, both indirectly and directly, the hyperglycemic state and oxygen delivery reduction through the vasa nervorum can determine inflammatory damage, which in turn is responsible for the alteration of the activity of the nerves. The symptoms and signs are therefore various, although symmetrical painful somatic neuropathy at the level of the lower limbs seems the most frequent manifestation. The pathophysiological aspects underlying the onset and progression of DN are not entirely clear. The purpose of this review is to shed light on the most recent discoveries in the pathophysiological and diagnostic fields concerning this complex and frequent complication of diabetes mellitus.

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Section: Diagnosismentioning

confidence: 99%

Peripheral Neuropathy in Diabetes Mellitus: Pathogenetic Mechanisms and Diagnostic Options

Galiero

Caturano

Vetrano

et al. 2023

IJMS

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“…The use of NDM improve physiological function which is reduce interneural oedema and decrease interneural pressure. It produced a DOI 10.18502/kme.v2i3.11854 ICMEDH significant reduction in pain, improvement of nerve conduction in sensory fibers and increase functional status [17,19].…”

Section: Discussionmentioning

confidence: 99%

The Impact of Neurodynamic Mobilization and Transcutaneous Electrical Nerve Stimulation on Pain Intensity in Cigarette Company Workers at Risk of Carpal Tunnel Syndrome

Utami

Astuti

Lubis

2022

Kme

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Indonesia is one of the largest cigarette producers and consumers in the world. Due to the repetitive activity and long hours experienced by cigarette manufacturer workers who roll the cigarettes, the risk of carpal tunnel syndrome (CTS) is high. They tend to experience pain, numbness and tingling through the hands and fingers. These symptoms occur following compression of the median nerve, which affects their functional ability. Neurodynamic mobilization (NDM) and transcutaneous electrical nerve stimulation (TENS) have been used as physical therapy in management of CTS. However, no studies have yet investigated the effect of the combination of both treatments and compared them. This was a quasi-experimental study with a pre-test post-test design, which compared the effect of a combination of NDM and TENS versus NDM only with cigarette company workers. The workers with the risk of CTS were divided into two groups: the combination NDM with TENS group and the NDM group. The interventions were applied 3 times a week for 1 month in both groups. The visual analogue scale (VAS) was used to measure the pain. The VAS scores were evaluated on the first day before the interventions were given and after 1 month. The Wilcoxon test was used to assess pre and post treatment. The Mann Whitney test was used to compare the effects of both interventions. According to the findings, both groups had a significant change in VAS measurement outcomes. The decrease in pain was larger in the NDM and TENS group than in the NDM group (p = 0.008). Carrying out a combination of NDM with TENS 3 times in a week for 1 month had a substantial impact on decreasing pain in cigarette workers with CTS risk Keywords: neurodynamic mobilization, TENS, carpal tunnel syndrome, pain, cigarette workers

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“…Although lack of blinding may introduce bias, it may be impossible for a manual therapist to perform treatment closely resembling the therapy under clinical settings while blinded (Kamper, 2018). A recent meta-analysis of six studies highlights the effectiveness of manual therapy techniques, including neuromoblisations, on improving pain, physical function and nerve conduction (Jiménez-Del-Barrio et al, 2022).…”

Section: Discussionmentioning

confidence: 99%

Manual therapy improves symptom severity and disability in patients with carpal tunnel syndrome

Wielemborek¹,

Kapica-Topczewska²,

Pogorzelski³

et al. 2022

Aktualn Neurol

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Aim: The aim of the study was to assess early outcomes of manual therapy in patients with carpal tunnel syndrome. Materials and methods: In this study, patients diagnosed with electrophysiologically confirmed carpal tunnel syndrome received manual therapy. The therapy was used in 41 individuals who received one session in line with IFOMPT (International Federation of Orthopaedic Manipulative Physical Therapists) standards per week for 5 weeks. Grip strength was assessed using a dynamometer, disability was assessed using the DASH (Disability of Arm, Shoulder and Hand) questionnaire, and the quality of life was assessed using VASEQ5D5L (Visual Analog Scale of the 5-level EQ-5D). Data was collected before the first treatment and one week after the last treatment. Results: We observed significant change in DASH score and quality of life. Grip strength tended to improve, but the effect was statistically significant only in patients over 50 years of age. Symptom severity (Carpal Tunnel 6 score, Douleur Neuropathique 4 score and peripheral cutaneous threshold assessed with Semmes–Weinstein monofilament) improved significantly. There was no significant correlation between changes in DASH score and grip strength. Conclusion: Manual therapy significantly improves quality of life and reduces upper limb disability in patients with carpal tunnel syndrome.

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The effectiveness of manual therapy on pain, physical function, and nerve conduction studies in carpal tunnel syndrome patients: a systematic review and meta-analysis

Cited by 30 publications

References 50 publications

Peripheral Neuropathy in Diabetes Mellitus: Pathogenetic Mechanisms and Diagnostic Options

Peripheral Neuropathy in Diabetes Mellitus: Pathogenetic Mechanisms and Diagnostic Options

The Impact of Neurodynamic Mobilization and Transcutaneous Electrical Nerve Stimulation on Pain Intensity in Cigarette Company Workers at Risk of Carpal Tunnel Syndrome

Manual therapy improves symptom severity and disability in patients with carpal tunnel syndrome

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