Family caregivers who provide care and support to cancer patients experience distress, burden, and decreased quality of life as a result of caregiving. Caregivers often turn to nurses for support, however there is little training available for nurses on how to care for the family caregiver. Undergraduate nursing students have a high need to learn about engaging caregivers in care, but little content is presented to fulfill that need. Derived from the COMFORT TM SM communication curriculum, we developed a one-hour online educational module specifically addressing communication with family caregivers of cancer patients. Undergraduate nursing students (n=128) from two accredited nursing programs completed a survey at the beginning and end of the module, in addition to answering unfolding response opportunities within the module. There was a significant increase in communication knowledge, attitude, behaviors (p,<.000) in post-test responses for students across all years of study. Knowledge based on responses to case study scenarios were more than 75% correct. Student open-ended responses to case-based scenarios featured in the module revealed student mastery and ability to apply module content (range, 40%-56% across four scenarios). This online COMFORT TM SM communication training module is an innovative online cancer education tool for teaching about communication with family caregivers. Conflict of Interest: The authors report no conflict of interest. Compliance with Ethical Standards: The authors disclose no conflicts of interest. Research involving human participants was approved by the University. Informed consent was obtained from all individual participants included in the study. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.