The Effectiveness of Arsenic Remediation from Groundwater in a Private Home

Pratson, Elizabeth Lewis; Vengosh, Avner; Dwyer, Gary S.; Pratson, Lincoln F.; Klein, E. M.

doi:10.1111/j.1745-6592.2009.01269.x

Cited by 18 publications

(13 citation statements)

References 4 publications

(2 reference statements)

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“…To lessen the risk of exposure to arsenic in drinking water, recommended preventative measures include point-of-use removal, modification of well depth, and/or use of an alternate water source (Alaerts and Khouri 2004; Pratson et al 2010). These solutions are rarely cost-effective, however, and may not be feasible in rural areas.…”

Section: Discussionmentioning

confidence: 99%

Arsenic in North Carolina: Public Health Implications

Sanders

Messier

Shehee

et al. 2012

Environment International

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Arsenic is a known human carcinogen and relevant environmental contaminant in drinking water systems. We set out to comprehensively examine statewide arsenic trends and identify areas of public health concern. Specifically, arsenic trends in North Carolina private wells were evaluated over an eleven-year period using the North Carolina Department of Health and Human Services (NCDHHS) database for private domestic well waters. We geocoded over 63,000 domestic well measurements by applying a novel geocoding algorithm and error validation scheme. Arsenic measurements and geographical coordinates for database entries were mapped using Geographic Information System (GIS) techniques. Furthermore, we employed a Bayesian Maximum Entropy (BME) geostatistical framework, which accounts for geocoding error to better estimate arsenic values across the state and identify trends for unmonitored locations. Of the approximately 63,000 monitored wells, 7,712 showed detectable arsenic concentrations that ranged between 1 and 806 μg/L. Additionally, 1,436 well samples exceeded the EPA drinking water standard. We reveal counties of concern and demonstrate a historical pattern of elevated arsenic in some counties, particularly those located along the Carolina terrane (Carolina slate belt). We analyzed these data in the context of populations using private well water and identify counties for targeted monitoring, such as Stanly and Union Counties. By spatiotemporally mapping these data, our BME estimate revealed arsenic trends at unmonitored locations within counties and better predicted well concentrations when compared to the classical kriging method. This study reveals relevant information on the location of arsenic-contaminated private domestic wells in North Carolina and indicates potential areas at increased risk for adverse health outcomes.

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Section: Discussionmentioning

confidence: 99%

Arsenic in North Carolina: Public Health Implications

Sanders

Messier

Shehee

et al. 2012

Environment International

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“…The interpretations of studies on the metabolic effects of arsenic are made difficult by the use of different doses and duration of exposure. Although the current MCL of arsenic stands at 10 ppb, higher levels of arsenic exposure continue to be an issue . We utilized a concentration that exceeds the MCL, and duration of exposure, though sufficient to be considered chronic, was relatively short.…”

Section: Discussionmentioning

confidence: 99%

Chronic Exposure to Low‐Dose Arsenic Modulates Lipogenic Gene Expression in Mice

Adebayo

Zandbergen

Kozul-Horvath

et al. 2014

J Biochem & Molecular Tox

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Arsenic, a ubiquitous environmental toxicant, can affect lipid metabolism through mechanisms that are not well understood. We studied the effect of arsenic on serum lipids, lipid-regulating genes, and transcriptional regulator sterol regulatory element binding protein 1c (SREBP-1c). C57BL/6 mice were administered 0 or 100 ppb sodium arsenite in drinking water for 5 weeks. Arsenic exposure was associated with decreased liver weight but no change in body weight. Serum triglycerides level fell in arsenic-exposed animals, but not in fed animals, after short-term fasting. Hepatic expression of SREBP-1c was reduced in arsenic-exposed fed animals, with a 16-fold change in reduction. Similar effects were seen for SREBP-1c in white adipose tissue. However, fasting resulted in dissociation of the expression of SREBP-1c and its targets, and SREBP-1c protein content could not be shown to correlate with its mRNA expression. We conclude that arsenic modulates hepatic expression of genes involved in lipid regulation through mechanisms that are independent of SREBP-1c expression.

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“…The analyses revealed that Melendiz Stream was carrying more arsenic to the lake. The conventional technologies that have been used to treat Ascontaminated water are coagulation (Karcher et al, 1999;Mamtaz and Bache, 2000;Baskan and Pala, 2009), adsorption to activated alumina (Bhattacharya et al, 2002;Spelman, 2003), ion exchange with strong-base anion-exchange resins (Spelman, 2003), and reverse osmosis (Bhattacharya et al, 2002;Pratson et al, 2010). The use of new adsorbents (Loukidou et al, 2003;Thirunavukkarasu et al, 2003;Pokhrel and Viraraghavan, 2006;Czerniczyniec et al, 2007;Sun et al, 2007;Su and Puls, 2008), in situ passive reactive barriers (Lindberg et al, 1997), bioremediation with chemical precipitation, and aquifer oxygenation are some of the emerging technologies for the in situ removal of As from groundwater.…”

Section: Processmentioning

confidence: 98%