“…This technique has been shown to stimulate left atrial receptors (Kidd, Ledsome & Linden, 1978) and has enabled Linden and his colleagues to define the reflex effects of stimulating such receptors in the anaesthetized dog. Stimulation of these receptors results in a reflex tachycardia (Furnival et al 1971) and an increase in urine flow (Ledsome & Linden, 1968) but no consistent changes in arterial blood pressure (Ledsome & Linden, 1964), peripheral resistance (Carswell, Hainsworth & Ledsome, 1970) or the pattern of breathing ) Subsequent work has shown that the distension of the atrial appendages (Kappagoda, Linden & Saunders, 1972b) and the junctions between the venae cavae and the right atrium (Kappagoda, Linden & Snow, 1972 a) also results in an increase in the heart rate.…”