The effect of zeolite on oxidant/antioxidant status in healthy dairy cows

Abstract

This study was conducted to evaluate the effect of dietary zeolite (clinoptilolite) supplementation on the oxidative/antioxidative status on plasma in healthy dairy cows. Twenty dairy cows were divided into two groups of 10. Control group was fed the basal ration for 60 days. Zeolite group was fed the basal ration supplemented with 2.5% zeolite daily. To evaluate the oxidative and antioxidative status comprehensively, indicators such as total oxidant status, oxidative stress index, total antioxidant status, lipid hydroperoxide, total free sulphhydryl groups, ceruloplasmin concentrations, arylesterase, paraoxonase-1 and catalase activities were measured in plasma. Lipid hydroperoxide concentration was significantly (P < 0.05) decreased from 6.21 ± 0.94 to 4.90 ± 1.05 mmol H 2 O 2 Eq/l by zeolite supplementation. However, no significant effect was observed on the antioxidant and other oxidant indicators. In conclusion, although zeolite decreased the lipid hydroperoxide concentration, it cannot further strengthen antioxidant defense system in healthy dairy cows. Clinoptilolite, oxidative stress, lipid hydroperoxide, total antioxidant status, dairy cattleThere are many stress factors impairing the health condition and performance of dairy cows. A common denominator of the responses to these stresses is the redox homeostasis. Redox homeostasis is maintained by the balance between production of reactive oxygen species (ROS) and antioxidant defense system. However, the level of ROS can exceed the antioxidant status of the animal leading to oxidative stress (Celli 2010). High producing dairy cows are prone to oxidative stress, and the situation can be exacerbated under certain environmental, physiological, and dietary conditions (Vazques-Anon et al. 2008).

Zeolite pretreatment accomplishes partial brain radioprotective role by reducing iron and oxidative / nitrosative stress in rats

“…•and NO 3 in all examined brain regions of rats on MZC supplemented diet can be explained by the ability of zeolites to bind transition metals (including metals participating in Fenton reaction, such as Fe) in the alimentary tract and reduce their availability to other organs. Very few studies on zeolite pointed at its indirect, antioxidant effect, confirmed by suppressed lipid peroxidation [5,32].…”

Effect of zeolite (Clinoptilolite) as a salinity stress alleviator on semen quality and hematobiochemical parameters of Montazah cocks under South Sinai conditions

“…However, it's worthy to reveal that zeolite groups had comparable total protein and globulin values with control group. Valpotic et al (2016) mentioned that zeolite improved the absorption of immunoglobulins, total proteins and some microelements, especially iron and copper in cow (Ipek et al, 2012). Moreover, Macháček et al (2010) demonstrated that differences in glucose and total protein as a result of clinoptilolite administration in feed (2% and 4%) of laying hen were not significant comparing to control ones and remained within the range of reference values.…”

Effect of Zeolite Addition on Physiological, Immunological, Reproductive and Productive Performance of Barki Ewes Under Water Salinity Stress in South Sinai, Egypt تأثير إضافة الزيوليت علي الأداء الفسيولوجى، المناعي، التناسلى والإنتاجى للنعاج البرقى تحت إجهاد ملوحة ماء الشرب فى جنوب سيناء

“…This decrease in SBR and MR from birth to weaning, on the other hand, might be linked to zeolite's adhesion-adsorption, ion-exchange, and cation binding characteristics (Ipek et al, 2012).…”