The effect of yogurt fortified with Lactobacillus acidophilus and Bifidobacterium sp. probiotic in patients with lactose intolerance

Abstract

This study assessed the effect of probiotic yogurt fortified with Lactobacillus acidophilus and Bifidobacterium sp. in patients with lactose intolerance. Fifty‐five patients suffering from lactose intolerance were randomly divided into control group of 28 lactose intolerance patients who received nonprobiotic yogurt (100 ml) and experimental group consisted of 27 lactose intolerance patients who received probiotic yogurt fortified (100 ml) with L. acidophilus and Bifidobacterium sp. Each individual received yogurt for one week. Lactose intolerance was confirmed when the patients received 75 g lactose and were positive after 30 min until 3 hr for lactose intolerance symptoms and by hydrogen breath test (HBT). After intervention, the hydrogen level was lower in experimental group in comparison with the control group. Lactose intolerance symptoms in experimental group were much less than the control group. Our findings revealed that probiotic yogurt fortified with L. acidophilus and Bifidobacterium sp. could safely and effectively decrease lactose intolerance symptoms and HBT, so our probiotic can be recommended as a treatment of choice in lactose intolerance patients.

The future of functional food: Emerging technologies application on prebiotics, probiotics and postbiotics

“…The beneficial effects related to probiotic intake by humans are many, such as reduction of the risk of diabetes (Wang et al., 2020), cardiovascular diseases (Vasquez et al., 2020), Crohn's disease (Lichtenstein et al., 2016), ulcerative colitis (Sandes et al., 2020), gastrointestinal disorders (Naseer et al., 2020), urogenital disease (Akgül & Karakan, 2018), liver diseases (Behrouz et al., 2020), and different types of cancer (Sieow et al., 2021). Furthermore, they can improve lactose intolerance (Masoumi et al., 2021), infection, allergies, immune system (Velez et al., 2021), respiratory infections (Robinson, 2018), oral health (Selvarajan et al., 2020), dermatitis (Kim et al., 2020), viral infections (Lopez‐Santamarina et al., 2021), physical activity (Jäger et al., 2020), among others.…”

The Gut Microbiota Influenced by the Intake of Probiotics and Functional Foods with Prebiotics Can Sustain Wellness and Alleviate Certain Ailments like Gut-Inflammation and Colon-Cancer

“…The health benefits offered by LAB are also nutritionally-therapeutic and include their role in vitamin production, allergies, and immunoregulation [ 52 ], the relief of lactose intolerance symptoms [ 53 ], the reduction in the risk of Crohn’s disease [ 54 ] and diabetes alleviation [ 55 ], or even have anti-cancer properties [ 56 ].…”

Complete Genome Sequence of Lactobacillus acidophilus LA-10A, a Promising Probiotic Strain Isolated from Fermented Mare’s Milk

“… Lactobacillus acidophilus is one of the commercially significant probiotics, originally isolated from the human gastrointestinal tract and designated Bacillus acidophilus in 1900 ( 1 ). L. acidophilus has been reported to play a pivotal role in maintaining human health by alleviating lactose intolerance ( 2 ), nonalcoholic fatty liver disease ( 3 ), irritable bowel syndrome ( 4 ), and hypercholesterolemia ( 5 ) and preventing Helicobacter pylori infection ( 6 , 7 ). Strain LA-10A was first isolated in 2016 from homemade fermented mare’s milk that was prepared by a shepherd in Xinjiang, China.…”