2022
DOI: 10.1016/j.prmcm.2021.100018
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The effect of Wogonoside on the expression of TGF-β1/Smad3 in Mycoplasma pneumoniae pneumonia

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“…Glycyrrhiza glabra belongs to the legume family, and its main chemical components are flavonoids, saponins, alkaloids, amino acids, coumarins, and polysaccharides [26] , which have anti-inflammatory, anti-tumor, anti-viral, hepatoprotective, and neuroprotective effects [27] . Modern pharmacological studies have confirmed that glycyrrhizin can effectively inhibit the release of inflammatory factors IL•1β and TNF•α from cells in Alzheimer's disease models [26] , and that glycyrrhizin and resveratrol glycosides have high binding power to dopamine receptor D3 (DRD3) and are thought to be potential drugs for the treatment of neurodegenerative diseases in Alzheimer's disease [28] . In a mouse model of depression, treatment with glycyrrhizin and isoglycyrrhizin significantly reduced the ratio of ISSN 2706-6819 Vol.5, Issue 1: 7-13, DOI: 10.25236/IJFM.2023.050102…”
Section: Licoricementioning
confidence: 99%
“…Glycyrrhiza glabra belongs to the legume family, and its main chemical components are flavonoids, saponins, alkaloids, amino acids, coumarins, and polysaccharides [26] , which have anti-inflammatory, anti-tumor, anti-viral, hepatoprotective, and neuroprotective effects [27] . Modern pharmacological studies have confirmed that glycyrrhizin can effectively inhibit the release of inflammatory factors IL•1β and TNF•α from cells in Alzheimer's disease models [26] , and that glycyrrhizin and resveratrol glycosides have high binding power to dopamine receptor D3 (DRD3) and are thought to be potential drugs for the treatment of neurodegenerative diseases in Alzheimer's disease [28] . In a mouse model of depression, treatment with glycyrrhizin and isoglycyrrhizin significantly reduced the ratio of ISSN 2706-6819 Vol.5, Issue 1: 7-13, DOI: 10.25236/IJFM.2023.050102…”
Section: Licoricementioning
confidence: 99%