The effect of vitamin D3 on the osteointegration of dental implant

Trybek, Grzegorz; Aniko-Włodarczyk, Magda; Kwiatek, Jakub; Preuss, Olga; Brodkiewicz, Andrzej; Sinicyn, Andrzej; Grzywacz, Anna

doi:10.29359/bjhpa.10.4.02

Cited by 13 publications

(8 citation statements)

References 13 publications

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“…The influence of vitamin D on physical health has been investigated over recent years [ 1 , 2 , 3 ]. Vitamin D is found in bones, kidneys, heart, brain, pancreas, intestines, muscles, and skin [ 4 , 5 ]. It regulates cell maturation, differentiation, and apoptosis [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Changes of 25(OH)D Concentration, Bone Resorption Markers and Physical Performance as an Effect of Sun Exposure, Supplementation of Vitamin D and Lockdown among Young Soccer Players during a One-Year Training Season

et al. 2022

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The main purpose of this research was to demonstrate the changes in 25(OH)D concentration, bone resorption markers, and physical fitness along the one-year training season in young soccer players. A total of 24 young soccer players (age: 17.2 ± 1.16 years, mass: 70.2 ± 5.84, height: 179.1 ± 4.26 cm) were tested at four different time points across one year (T1—September 2019; T2—December 2019; T3—May 2020; T4—August 2020). After T2 (during COVID-19 lockdown), players were divided into a supplemented (GS) group and a placebo group (GP). Variables such as 25(OH)D, calcium (Ca), phosphorus (P), parathyroid hormone (PTH), aerobic capacity, speed, and explosive power were measured. Analyses performed for all participants indicated significant changes in all selected blood markers and running speed. The highest values in 25(OH)D were noted during summertime in T1 and T4. After individuals were split into two groups, a two-factorial ANOVA demonstrated a significant time interaction for 25(OH)D, Ca, P, PTH, 30 m sprint, and counter-movement jump. Significant time x group effect was calculated for aerobic capacity. This study confirmed that 25(OH)D concentration varies between four seasons, with the greatest decreases in the low sunlight periods. Vitamin D supplementation did not cause a preventive and long-lasting effect of increasing the 25(OH)D concentration in the young soccer players.

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Section: Introductionmentioning

confidence: 99%

Changes of 25(OH)D Concentration, Bone Resorption Markers and Physical Performance as an Effect of Sun Exposure, Supplementation of Vitamin D and Lockdown among Young Soccer Players during a One-Year Training Season

et al. 2022

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“…Vitamin D has also been found to be essential for the maturation and proper functioning of bone cells by the production of a factor stimulating osteoclast precursor fusion and stimulation of osteoblast differentiation. Vitamin D also increases osteoid mineralization [37]. Also, this mechanism can play an important role in the stabilization phase of the implant, after stabilization is achieved by loading it with a prosthetic crown.…”

Section: Biomed Research Internationalmentioning

confidence: 99%

The Possible Role of Vitamin D Deficiency in Early Implant Failure

Hakim

Ghasemi

Bashar

et al. 2021

BioMed Research International

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Background. Dental implants are one of the most successful treatments for restoring tooth function and beauty. Identifying the causes of dental implant failure is useful and vital. This review was aimed at studying the possible role of vitamin D in early implant failure. Method and Material. This review was designed based on the PRISMA guideline. Data was collected using keywords including implant, vitamin D, deficiency, failure, dental, OR tooth in international databases including PubMed, Scopus, Web of Science, Cochrane, and Embase, until 2020. Based on the inclusion and exclusion criteria, data were extracted and gathered in a checklist. Results. Finally, twelve studies were selected from five different countries. In 6 studies (2 animal studies and four human studies), there was no significant relationship between vitamin D deficiency and dental implant failure. In the other six studies (1 animal study and five human studies), there was a significant relationship in this regard. Conclusion. It is difficult to conclude the association between vitamin D and implant failure based on the literature’s researches. However, vitamin D appears to play an essential role in implant success through its effects on immune system modulation.

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“…During the postsurgical phase and also after loading the implant with a prosthetic restoration, the subsequent influence of vitamin D metabolites on the processes of homeostasis with bone tissue adjacent to the implant surface, which determines the correct induction of osteoclasts and osteoblasts, is particularly important [ 19 ]. The function of vitamin D reducing inflammation around the implant is also particularly noteworthy.…”

Section: Introductionmentioning

confidence: 99%

“…The function of vitamin D reducing inflammation around the implant is also particularly noteworthy. In addition, at the boundary between the implant and the prosthetic crown, vitamin D induces regional cells of the immune system (e.g., production of 1-alpha-hydroxylase by monocytes) [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

Impact of the 25-Hydroxycholecalciferol Concentration and Vitamin D Deficiency Treatment on Changes in the Bone Level at the Implant Site during the Process of Osseointegration: A Prospective, Randomized, Controlled Clinical Trial

Kwiatek

Jaroń

Trybek

2021

JCM

Self Cite

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Introduction: The most important factor which is responsible for the positive course of implant treatment is the process of osseointegration between the implant structure and the host’s bone tissue. The aim of this study was to assess what effect the 25-hydroxycholecalciferol concentration and vitamin D deficiency treatment have on changes in the bone level at the implant site during the process of osseointegration in the mandible. Materials and Methods: The study was with 122 people qualified for implant surgery, who were assigned to three research groups (A, B, and C). Laboratory, clinical, and radiological tests were performed on the day of surgery, and after 6 and 12 weeks. The bone level in the immediate proximity of the implant was determined by radiovisiography (RVG). Results: The bone level after 12 weeks in Groups B and C was significantly higher than after 6 weeks. The bone level in the study Group B was significantly higher than in Group A. The study showed that the higher the levels of 25-hydroxycholecalciferol were observed on the day of surgery, the higher was the level of bone surrounding the implant after 6 and 12 after surgery. Conclusion: The correct level of 25-hydroxycholecalciferol on the day of surgery and vitamin D deficiency treatment significantly increase the bone level at the implant site in the process of radiologically assessed osseointegration.

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The effect of vitamin D3 on the osteointegration of dental implant

Cited by 13 publications

References 13 publications

Changes of 25(OH)D Concentration, Bone Resorption Markers and Physical Performance as an Effect of Sun Exposure, Supplementation of Vitamin D and Lockdown among Young Soccer Players during a One-Year Training Season

Changes of 25(OH)D Concentration, Bone Resorption Markers and Physical Performance as an Effect of Sun Exposure, Supplementation of Vitamin D and Lockdown among Young Soccer Players during a One-Year Training Season

The Possible Role of Vitamin D Deficiency in Early Implant Failure

Impact of the 25-Hydroxycholecalciferol Concentration and Vitamin D Deficiency Treatment on Changes in the Bone Level at the Implant Site during the Process of Osseointegration: A Prospective, Randomized, Controlled Clinical Trial

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