The Effect of Urea Nitrogen/Creatinin Ratio Level on in Hospital Mortality and One Year Mortality of Patients with ST Segment elevation Myocardial Infarction undergone thrombolytic therapy

Abstract

Introduction & Objective: Considering the increasing prevalence of ST-elevation myocardial infarction (STE-MI) and its health care costs and clinical consequences, as well as the fact that kidney problems are among the most common cases in these patients, treatment system and the evaluation of its functional improvement will be considered, Therefore, in the present study, we intend to investigate the effect of blood urea nitrogen to creatinin ratio (BUN/Cr) on in-hospital mortality (IHM) and one-year mortality of patients diagnosed with STEMI undergoing thrombolytic treatment. Materials and Methods: This descriptive cross-sectional descriptive study was conducted in in Shahid Madani, University of Medical Science, Tabriz, Iran in 2021. A list of patients diagnosed with STEMI and received thrombolytic treatments in 2017- 2019 were compiled. The file was included in the study and analyzed taking into account the inclusion and exclusion criteria. A checklist was used to collect the data. Data were analyzed using SPSS-15 software and descriptive and inferential statistics. Results: The results of the present study showed that blood BUN/Cr tolevel had no association with IHM and one-year mortality of STEMI patients who underwent thrombolytic treatment. There was also no association between the BUN/Cr ratio and in-hospital complications such as heart failure (HF) and cardiogenic shock (CS). Conclusion: we found that BUN/Cr ratio is not a reliable prognostic factor for mortality and hospital complications in STEMI patients.