The effect of ultraviolet radiation of pancreatic exocrine cells in mole rats: An ultrastructural study

Abstract

UltrastructureMole rats a b s t r a c tThe purpose of this study was to investigate the ultrastructural effects of ultraviolet C (UVC) radiation on the pancreatic exocrine cells of mole rats. The mole rats were divided into two groups as control and test groups. Control group did not receive any radiation. The other group was irradiated with UV radiation for 14 and 28 days. The pancreatic tissue samples were prepared and then analyzed through transmission electron microscope.Depending on the radiation exposure, it is likely to say that the zymogen granules decreased to more than 70 per cent for the control group and the dilation of rough endoplasmic reticulum and vacuolization of mitochondria increased in the pancreatic exocrine cells at the 14 days of radiation as compared with the control group; however, they were easily observed in the 28 days of radiation exposure. Particularly in the 28 days of radiation, the zymogen granules decreased and vacuolated, and the rough endoplasmic reticulum was frequently shortened and dilated. These findings clearly demonstrated the effects of UVC radiation on pancreatic exocrine cells in an exposure-period dependent manner.

Toxicity Effect of Ultraviolet (UV) Radiations on the Human Germ Cell and the Protective Role of Vitamin E

“…The effects of UVR on the pancreatic exocrine cells of male rats were examined by the electron microscope [28]. Its clearly demonstrated, particularly in the 28 days of radiation, the zymogen granules decreased and vacuolated, and the rough endoplasmic reticulum was frequently shortened and dilated.…”

“…The level of radiation effects on the living beings damage depends on the radiation dose received, absorbed dose and under certain exposure conditions, harmful effects of radiations may or may not occur [28]. The deformation in the cells could develop depending on the dosage and the period exposal of the radiation applied [33][34][35].…”

The ameliorative effect of gallic acid on pancreas lesions induced by 2.45 GHz electromagnetic radiation (Wi-Fi) in young rats

“…Sakurai et al reported that glucose-stimulated insulin secretion was decreased by EMR exposure (Sakurai, Koyama, Komatsubara, Jin, & Miyakoshi, 2005). Turker (2015) showed that EMR can cause ultrastructural changes in endocrine cells in the pancreas. EMR has also been shown to increase the diabetogenic effect of alloxan in mice (Garyae, Kokaya, Mukhina, Leonova-Garyaeva, & Kokaya, 2007).…”