The effect of ultrasound‐assisted thrombolysis studied in blood‐on‐a‐chip
Yan Li,
Yongjian Li,
Haosheng Chen
Abstract:BackgroundThromboembolism, which leads to pulmonary embolism and ischemic stroke, remains one of the main causes of death. Ultrasound‐assisted thrombolysis (UAT) is an effective thrombolytic method. However, further studies are required to elucidate the mechanism of ultrasound on arterial and venous thrombi.MethodsWe employed the blood‐on‐a‐chip technology to simulate thrombus formation in coronary stenosis and deep vein valves. Subsequently, UAT was conducted on the chip to assess the impact of ultrasound on … Show more
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