“The effect of two different intravitreal injection techniques on frequency of vitreous reflux and on treatment response in neovascular AMD patients”

Erdem, Burak; Kaptı, Hasan Burhanettin

doi:10.1016/j.jfo.2021.10.005

Journal Français d'Ophtalmologie

2022

DOI: 10.1016/j.jfo.2021.10.005

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“The effect of two different intravitreal injection techniques on frequency of vitreous reflux and on treatment response in neovascular AMD patients”

Burak Erdem

Hasan Burhanettin Kaptı

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2024

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Effect of Vitreous Reflux after Intravitreal Aflibercept Injection for Macular Edema with Branch Retinal Vein Occlusion: A Real‐World Study

Muto,

Sakamoto,

Machida

et al. 2024

Journal of Ophthalmology

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Purpose. This study aimed to evaluate the therapeutic effect of vitreous reflux (VR) after intravitreal aflibercept injection (IVAI) for macular edema (ME) following naïve branch retinal vein occlusion (BRVO). Methods. Eighty patients with ME following BRVO were divided into three groups according to the conjunctival bleb diameter after IVAI as follows: group A (no VR), group; B (<3 mm VR), and group C (>3 mm VR). Each patient received single IVAI. The treatment response was evaluated with the best‐corrected visual acuity (BCVA) and optical coherence tomography measurements of the retinal foveal thickness (RFT) before treatment and 1 month after the first injection. RFT >375 μm was defined as recurrence and received additional IVAI. The recurrence rate of ME and total numbers of IVAI were investigated at 12 months. Results. The BCVA values at 1 month were 0.17 ± 0.29 in group A (n = 41), 0.18 ± 0.17 in group B (n = 18), and 0.19 ± 0.26 in group C (n = 21). The RFT at 1 month were 270 ± 45 μm in group A, 279 ± 24 μm in group B, and 290 ± 43 μm in group C, respectively. ME recurred in 29 out of 41 patients in group A, 15 out of 18 in group B, and 14 out of 21 in group C. The total numbers of IVAI were 2.50 ± 1.24 in group A, 2.59 ± 1.06 in group B, and 2.29 ± 1.27 in group C, respectively. In the abovementioned comparisons, no significant differences were found following an IVAI (P > 0.05). Conclusions. VR after IVAI did not affect the therapeutic effect in patients with ME following BRVO. Thus, we do not need to pay excess attention to VR in the case of IVAI.

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Effect of Vitreous Reflux after Intravitreal Aflibercept Injection for Macular Edema with Branch Retinal Vein Occlusion: A Real‐World Study

Muto,

Sakamoto,

Machida

et al. 2024

Journal of Ophthalmology

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“The effect of two different intravitreal injection techniques on frequency of vitreous reflux and on treatment response in neovascular AMD patients”

Cited by 1 publication

References 13 publications

Effect of Vitreous Reflux after Intravitreal Aflibercept Injection for Macular Edema with Branch Retinal Vein Occlusion: A Real‐World Study

Effect of Vitreous Reflux after Intravitreal Aflibercept Injection for Macular Edema with Branch Retinal Vein Occlusion: A Real‐World Study

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