The Effect of Twin Birth on Neonatal and Infant Mortality Rates: A Systematic Review

Jafarian, Saleh; Amiri, Masoud; Mobasheri, Mahmoud

doi:10.15171/ijer.2018.24

Cited by 3 publications

(2 citation statements)

References 17 publications

(32 reference statements)

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“…Our data demonstrated that preterm birth was among the most important factors associated with neonatal death. Globally, preterm birth is the most common cause of death in children under five (14,27). Similar to other studies, the mean gestational age of the neonates in the present study was 30 weeks, indicating that most dead neonates were premature (3,8).…”

Section: Discussionsupporting

confidence: 89%

Causes, Timing, and Factors Related to Neonatal Death: A Descriptive Study

Varzeshnejad,

Najari,

Khoshnood Shariati

et al. 2023

J Compr Ped

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Background: Neonatal and pediatric health have a great share in global health programs. However, the neonatal mortality rate still shows unacceptable figures and statistics worldwide. Objectives: To investigate the timing and causes of neonatal death. Methods: In this retrospective descriptive study conducted in neonatal care units of Mahdiyeh Hospital in Tehran, Iran, the census sampling method was used to include all the medical records of the expired neonates during 2015-2020. Neonatal and maternal demographics and health complications were recorded. Descriptive statistics such as mean, standard deviation, frequency, and associations were analyzed to compare factors recorded as causes of neonatal death and its timing. A P-value of < 0.05 was considered significant. Results: Out of 24049 live births, 755 neonates had expired (3.1%). The expired neonates' average birth weight was 1616 ± 905 grams, and 35.9% weighed under 1000 grams. Most (80.8%) expired neonates were preterm (30.9 ± 4.8 gestational weeks), and the most common causes of neonatal death were prematurity (23.6%), congenital anomaly (19.9%), respiratory distress syndrome or RDS (19.5%), sepsis (13.2%), and asphyxia (7%). Most (60.7%) neonates died between the second and seventh days of birth. The following conditions were associated with an early-period neonatal death rather than a later-period: multiple births (OR = 2.8), normal vaginal delivery (OR = 2.03), low-birth-weight, diabetic mothers, neonatal heart disease, neonatal neurological diseases, RDS, asphyxia, familial marriage, and intrauterine growth restriction (IUGR) (P < 0.05). Being male (P = 0.005) or being multiple births (P < 0.0001) were associated with a higher risk of death. While 57% of mothers delivered through Cesarean section, among the expired neonates, 66.9% were delivered through Cesarean section. In expired neonates, Apgar scores were low in the first (5.71) and fifth (7.27) minutes of birth. Conclusions: Our study showed that prematurity, congenital anomaly, RDS, sepsis, and asphyxia were the most prevalent causes of death among expired neonates, respectively. Preterm birth and low birth weight were prevalent among expired neonates. Conducting regular similar studies periodically is important to identify, manage, and reduce neonatal mortality rates as an indicator of health promotion in the country.

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Section: Discussionsupporting

confidence: 89%

Causes, Timing, and Factors Related to Neonatal Death: A Descriptive Study

Varzeshnejad,

Najari,

Khoshnood Shariati

et al. 2023

J Compr Ped

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“…Furthermore, with the widespread development of assisted reproductive technique, the incidence of monozygotic twins has increased significantly 28. The NMR of twins is several times higher than that of singletons 29–31…”

Section: Discussionmentioning

confidence: 99%

Neonatal mortality and leading causes of deaths: a descriptive study in China, 2014–2018

Liu

Kang

et al. 2021

BMJ Open

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ObjectiveThe present study estimated the national and urban–rural levels and causes of neonatal deaths in China annually between 2014 and 2018 to provide data support for the further end of preventable neonatal deaths for China and other low-income and middle-income countries.MethodsThe study was based on data from the National Maternal and Child Health Surveillance System. All neonates of surveillance districts (gestational week: ≥28 weeks) who died after delivery have been involved in the study. The mortality rate and the leading causes of death for neonates were analysed.ResultsThe neonatal mortality rate (NMR) of China has steadily decreased from 5.9 deaths per 1000 live births in 2014 to 3.9 deaths per 1000 live births in 2018. The NMR in 2018 of urban and rural areas was 2.2 deaths per 1000 live births and 4.7 deaths per 1000 live births, respectively. The leading preventable causes of neonatal deaths are the same in the urban and rural areas were same, which were preterm birth, intrapartum complications and pneumonia. Mortality rates of these three causes fell significantly between 2014 and 2018 but contributed to a higher proportion of deaths in rural areas than urban areas. The proportion of preventable deaths accounted for 74.6% in 2018.ConclusionsThe NMR of China has decreased steadily from 2014 to 2018. However, the inequality between urban and rural areas still exists. The goal of government interventions should be to reduce the health inequality of neonates and further take targeted measures to eliminate preventable neonatal death.

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