Abstract:Background: Open cranial vault reconstruction is the standard technique of craniosynostosis correction that may cause significant blood loss. Objectives: The current study aimed at comparing the effect of tranexamic acid (TXA), controlled hypotension, and their combination on perioperative blood loss and transfusion requirement in craniosynostosis surgery. Methods: The present randomized, double-blind clinical trial was conducted on 75 infants referred for craniosynostosis surgery during 2017 - 2018. Ten minut… Show more
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