The effect of total fasting on thyroid function in man

The Effect of Acute Iodide Depletion on Thyroid Function in Man*

“…Estimates of the concentration of iodide in plasma were decreased in all four patients studied during mannitol diuresis and had decreased even further by the time of the postdiuresis test. In the remain4These doubts concerning the efficacy of simple fasting as a means of inducing uncomplicated iodide depletion have recently been verified by studies which have demonstrated that a total fast of 1 to 3 days duration not only fails to decrease the iodide concentration in plasma, but also leads to decreases in both thyroid iodide clearance rate and absolute iodine accumulation (38). Several indexes provided evidence that thyroid function had increased as a consequence of the iodide depletion procedures carried out.…”

The interpretation of the serum protein-bound iodine: A review

“…However, a tendency towards low serum PBI levels has been reported in obese patients whose serum free fatty acid level was not reduced by adrenaline (Goldberg and Gordon, 1964). In one group of obese patients fasting lowered the serum PBI level by The interpretation of the serum protein-bound iodine: A review 1 ,tg/100 ml and also lowered the thyroid absolute iodine uptake (Alexander, Harrison, Harden, and Koutras, 1964). In another group of obese patients fasting was found not to affect the serum PBI (Schatz, Sheppard, Palter, and Jaffri, 1967).…”

Thyroid Dysfunction in Chronic Renal Failure

“…Goiter may be induced by the high serum level of inorganic iodide (1,2,10) or retention of goitrogenic substances normally excreted by the kidney (11). Finally, malnutrition may be a contributing factor in altering thyroid function tests (12).…”