The effect of Thymus vulgaris on growth and biofilm formation of uropathogenic Escherichia coli

Flores-Encarnación, Marcos; Nava-Nolazco, R M; Aguilar-Gutiérrez, Germán Rubén; Carreño-López, Ricardo; Carreno-LÃ3opez, R

doi:10.5897/ajmr2017.8770

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…Antibiotic overuse can lead to bacterial resistance, resulting in infections caused by antibiotic resistant bacteria, which is a serious increasing issue. (Flores-Encarnación et al, 2018). The global threat of resistance to antibiotics, according to WHO, is going to usher in a post-antibiotic period.…”

Section: Resultsmentioning

confidence: 99%

Investigation of the Role of Vitamin C In Enhancing the Activity of Antibacterial Agents and Biofilm Formation

Younis

Ali

Najem

2021

EPSTEM

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Resistance to antibiotics is rapidly spreading across the globe, posing a new health-care challenge for all countries. Bacterial biofilms are three-dimensional formations made up of cells encased in a matrix of polymeric, making cells resistant to the drugs and the immune system. As a result, new tactics for inhibiting the production of the EPS matrix may lead to more efficient use of already available antibiotics. The mechanism of vitamins C effect on boosting the effectiveness of several anti-bacterial drugs was investigated in this study, the target isolates were obtained from University of Mosul/ Biology department/ bacterial culture collections and evaluated qualitatively and quantitatively. The isolates involved: Staphylococcus aureus, Escherichia coli ,Klebsiella sp., Serratia marcescens and Pseudomonas aeroginosa. Antibiotic sensitivity tests and biofilm producing assay results revealed that the majority of the isolates were resistant to a range of antibiotics and had a large capacity for biofilm formation when grown on a cover glass surface. Vitamin C is an antioxidant, a scavenger of active metabolites. The Minimum Inhibitory Concentration (MIC) of Vitamin C against selected isolates had been determined, and all further experiments used concentrations below the MIC. Our results showed that Vit.C pre-treatment enhance the bactericidal effect of antibiotic and increases bacterial susceptibility to antibiotics. Using light microscopy, experiments of sub inhibitory doses of Vitamin C revealed good suppression of selected isolates biofilm development on the cover glass surface. Vitamin C can be utilized as an antibiotic adjuvant in combination with antibiotic and has effective biofilm inhibition, caused by multidrug-resistant bacteria, according to evidence.

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Section: Resultsmentioning

confidence: 99%

Investigation of the Role of Vitamin C In Enhancing the Activity of Antibacterial Agents and Biofilm Formation

Younis

Ali

Najem

2021

EPSTEM

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“…The essential oil of T. vulgaris has been shown to limit bacterial growth and possesses powerful bactericidal activities, including activity against antibiotic-resistant strains. Also, it has been shown to inhibit bacterial colonization and biofilm development on surfaces by uropathogenic E. coli (Flores-Encarnación, 2018). There are only a few reports on the bactericidal action of T. vulgaris essential oil.…”

Section: Thymementioning

confidence: 99%

Nanotechnology and Its Prospective Role in Using Bioactive Compounds to Fight Covid 19 Infection in This Era

Hamdy,

El Sayed,

Allm

et al. 2023

Egyptian Journal of Desert Research

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TIs or pneumonia, which account for 15% of all pediatric fatalities under the age of five and cause significant morbidity, continue to be a serious global health issue. The most dangerous infection lately COVID-19 associated with bacterial superinfections, which results in a fatal acute respiratory infection marked by shortness of breath. Scientists continue to face significant challenges in the development of vaccines and antiviral or antibacterial medications to treat these diseases. Recently, Bioactive natural products from a variety of plants and organisms, such as bacteria, fungi, and algae, hold promise as treatments for cancer, bacterial infections, inflammatory diseases, and other medical conditions. To facilitate the transport of these bioactive compounds to a particular target, nanoparticles drug delivery system can be adopted. Nanotechnology has been recognized as an essential tool in vast human medical fields. The goal of this review is to highlight prior and ongoing research on naturally occurring active nanomaterials as antiviral or antimicrobial agents, particularly for diseases of the modern era like COVID-19, and to R 514 Naglaa M. Hamdy et al.

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The effect of Thymus vulgaris on growth and biofilm formation of uropathogenic Escherichia coli

Cited by 2 publications

References 14 publications

Investigation of the Role of Vitamin C In Enhancing the Activity of Antibacterial Agents and Biofilm Formation

Investigation of the Role of Vitamin C In Enhancing the Activity of Antibacterial Agents and Biofilm Formation

Nanotechnology and Its Prospective Role in Using Bioactive Compounds to Fight Covid 19 Infection in This Era

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