2021
DOI: 10.1158/1055-9965.epi-20-0984
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The Effect of the Variability in Fecal Immunochemical Test Sample Collection Technique on Clinical Performance

Abstract: Background: Fecal immunochemical test (FIT) performance can be affected by post-collection variables. Collection technique might also affect fecal hemoglobin concentration (f-Hb). Variation in quantity of feces collected in samples returned in a colorectal cancer detection program, and the effects of under-sampling, were assessed.Methods: Collection devices obtained from patients undergoing FIT were assessed for the color (in five classes) of the feces in buffer, mass, and f-Hb. Associations between these were… Show more

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Cited by 6 publications
(2 citation statements)
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“…As part of the SCOOP program, 15 if an interval FIT returned a positive result, the next colonoscopy was completed sooner than scheduled, while those returning a negative FIT had colonoscopies performed as scheduled. Complete details about the faecal tests have been previously published 16 …”
Section: Methodsmentioning
confidence: 99%
“…As part of the SCOOP program, 15 if an interval FIT returned a positive result, the next colonoscopy was completed sooner than scheduled, while those returning a negative FIT had colonoscopies performed as scheduled. Complete details about the faecal tests have been previously published 16 …”
Section: Methodsmentioning
confidence: 99%
“…Many people, especially older adults or people who are participating in CRC screening for the first time, might be more likely to have the non-standard sample collection. Unqualified fecal sample collection could lead to a false-negative qFIT result ( 24 ), delay further diagnostic colonoscopy, and even cause death. To avoid the influence of low-quality sample collection, increasing sample collection operant training would contribute to the diagnostic efficiency of the qFIT in CRC screening.…”
Section: Introductionmentioning
confidence: 99%