The Effect of the Drug “Enterocol” on the Humoral Factors of Calf Body Resistance

Abstract

| As world experience shows, of particular importance in the prevention and treatment of gastrointestinal diseases of young animals is replacement therapy, aimed at restoring intestinal biocenosis through the regulatory injection of live bacteria representing the normal intestinal microflora. Currently, the veterinary service has a sufficient number of domestic and imported probiotic products of various species composition, intended for the prevention of gastrointestinal diseases of young animals and birds. However, monitoring of the probiotic market shows that the vast majority of developments are not in demand by practice. This circumstance gives grounds to assume that the approach to the development of probiotics should be based on the study of many parameters, including, first of all, a comprehensive assessment of the properties of microorganisms -probionts. The article presents the results of studying the effect of "Enterocol" from the strain E.coli 64G on the total amount of protein, quantitative and qualitative content of immunoglobulins in the blood serum of newborn calves. It was found that feeding off of the newborn calves with "Enterocol" helped to increase the concentration of total protein and immunoglobulins of all classes in the blood. The authors of the study came to the conclusion that the degree of the above increase depends on the dose of the drug given. Citation | Bulegenova M, Biyashev K, Kirkimbaeva Z, Biyashev B, Ermagambetova S, Oryntayev K, Altenov A (2019). The effect of the drug "enterocol" on the humoral factors of calf body resistance. Adv. Anim. Vet. Sci. 7(8): 674-680.

Determination of prophylactic and therapeutic effectiveness of probiotic strain Escherichia coli 39-SN

“…Considering the disadvantages of probiotic drugs, the authors intended to develop a competitive treatment and prophylactic drug based on probiotic bacterial strains. When designing new probiotic preparations, it is necessary to consider quantities of various strains in the intestine, their physiological features, and their ability to survive in aggressive conditions (acidic stomach environment, bile acids) [ 1 ]. Furthermore, to increase the efficiency of preparations, it is important to select prebiotic correctly, an essential supplement for probiotic preparations, and a source of food for weakened representatives of intestinal microflora of the patient.…”

“…For example, only in Kazakhstan, 18 biological products of this class are registered and used in medical practice, and in the European Union (EU) countries, more than 20 probiotics. These drugs are different in composition, quality, pharmacological action, and indications for use [ 1 – 3 ]. However, monitoring the probiotic market shows that most developments are not in demand since, in some cases, probiotics do not correspond to the properties declared by the manufacturer.…”

Optimization of urolithiasis treatment and diagnosis in the Turkestan region

“…To date, the use of potassium citrate has become one of the cornerstones in the treatment of nephrolithiasis. The results of Bulegenova et al [ 39 ], Banyra et al [ 40 ], Biyashev et al [ 41 ] indicated a long-term effect of this drug on the metabolic parameters of urine analysis in patients with urate calculi and a positive effect on the rate of formation. At the Center for the Study of Kidney Stones at the Ducan University Medical Center (USA) during 2000–2006, a retrospective cohort study was conducted among patients who had 24-hour urinalysis results before and after therapy and who continued potassium citrate treatment for at least 6 months (1480 people in total).…”

Improved Efficiency of Bluetongue Viral Antigen Isolation for Successful Immunization

“…Currently, 27 BTV serotypes have been identified, with limited serological cross-neutralization and cross-protection similarities (Ries et al 2020). Sheep, cattle, deer, camels, buffaloes, goats, and other wild ruminants are susceptible to BTV infection in their natural habitat (Zhumanov et al 2015;Bulegenova et al 2019). In susceptible animals, the disease is characterized by fever and hemorrhagic mucus membranes, which develop into inflammatory necrotic lesions in the mouth, tongue, gastrointestinal tract, corolla epithelium, the base of hooves, and swelling of the intermaxillary space and chest (Matthews et al 2022;Selim et al 2022).…”