The effect of supplementing the calcium phosphate cement containing poloxamer 407 on cellular activities
Yeeun Kim,
Kenichi Hamada,
Kazumitsu Sekine
Abstract:Calcium phosphate cement (CPC) is generally used for bone repair and augmentation. Poloxamers are tri‐block copolymers that are used as surfactants but have applications in drug and antibiotic delivery. However, their biological effects on bone regeneration systems remain unelucidated. Here, we aimed to understand how supplementing the prototype CPC with poloxamer would impact cellular activity and its function as a bone‐grafting material. A novel CPC, modified beta‐tricalcium phosphate (mβ‐TCP) powder, was de… Show more
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