The Effect of Sugammadex on Respiratory Functions in Bariatric Surgery

Abstract

Objective: Bariatric surgeries increased in the last decades likewise obesity. The need for high doses of neuromuscular blocking agents in these surgeries may cause residual paralysis and critical respiratory events and late complications such as hypoxemia, pneumonia, atelectasis, and the possibility of reintubation. The purpose of this study to evaluate the effect of sugammadex on respiratory parameters.Materials and method: 62 patients are included the study and they were assigned to one of the two groups randomly. LSG operation was performed on all the patients based on standard anesthesia management. In Group S (n=31), Sugammadex 2mg/kg was administered for the reversal of rocuronium. In Group N (n=31), Neostigmine 0.05mg/kg was administered together with atropine 0.02mg/kg for the reversal of rocuronium. Extubation duration, Aldrete scores at 5, 10, and 15 minutes after extubation, PACU duration, FEV1 values of RFT, ABG values, mobilization time were analyzed.Results: In group S, patients have higher PO2 and lower PCO2 levels, shorter mobilization times, and an Aldrete score of 15 sooner, and moreover, they occupy the operating room and PACU to a lesser extent but FEV1 values did not differ between groups. Conclusion:In conclusion, sugammadex allows a safe and rapid recovery from deep rocuronium-induced neuromuscular blockade after LSG surgery.